Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2B6 | P20813 | 1/20 | 0.89 |
| ▸ | CYP19A1 | P11511 | 14/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11047050 | 0.96 | CYP2B6 (0.96) | CYP2B6CYP19A1TBXAS1CYP11B1CYP11B2 | |
| SCHEMBL11046868 | 0.94 | CYP2B6 (1.00) | CYP2B6CYP19A1TBXAS1 | |
| SCHEMBL11046639 | 0.94 | CYP2B6 (1.00) | CYP2B6CYP19A1TBXAS1 | |
| SCHEMBL20076324 | 0.94 | CYP2B6 (1.00) | CYP2B6CYP19A1TBXAS1 | |
| SCHEMBL570574 | 0.94 | CYP2B6 (1.00) | CYP2B6CYP19A1TBXAS1 | |
| SCHEMBL11047040 | 0.94 | CYP2B6 (1.00) | CYP2B6CYP19A1TBXAS1 | |
| Iodide SCHEMBL16164466 | 0.92 | CYP2B6 (0.96) | CYP2B6CYP19A1TBXAS1 | |
| Hydrochloric Acid SCHEMBL11047046 | 0.92 | CYP2B6 (0.96) | CYP2B6CYP19A1TBXAS1 | |
| Water SCHEMBL29258020 | 0.92 | CYP2B6 (0.96) | CYP2B6CYP19A1TBXAS1 | |
| SCHEMBL3019994 | 0.91 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4284641-A | ANTITHROMBOEMBOLIC AGENT | BURROUGHS WELLCOME CO. (US) | 1981-08-18 | — | — | US | claimed |
| EP-0000950-A1 | Imidazole derivatives and salts thereof and their synthesis | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-03-07 | — | — | EP | claimed |
| EP-0000951-B1 | PHARMACEUTICAL FORMULATIONS COMPRISING 1-SUBSTITUTED IMIDAZOLES, 1-SUBSTITUTED IMIDAZOLES AND 1-SUBSTITUTED IMIDAZOLES FOR USE IN THE TREATMENT OR PROPHYLAXIS OF THROMBO-EMBOLIC DISORDERS | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-05-23 | — | — | EP | disclosed |
| EP-0000950-B1 | IMIDAZOLE DERIVATIVES AND SALTS THEREOF AND THEIR SYNTHESIS | THE WELLCOME FOUNDATION LIMITED (GB) | 1984-02-01 | — | — | EP | disclosed |
| US-4317830-A | ANTISHOCK AGENTS, ANTICOAGULANTS | BURROUGHS WELLCOME CO. (US) | 1982-03-02 | — | — | US | disclosed |
| US-4284641-A | ANTITHROMBOEMBOLIC AGENT | BURROUGHS WELLCOME CO. (US) | 1981-08-18 | — | — | US | disclosed |
| EP-0000950-A1 | Imidazole derivatives and salts thereof and their synthesis | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-03-07 | — | — | EP | disclosed |
| EP-0000951-A1 | Pharmaceutical Formulations comprising 1-substituted imidazoles, 1-substituted imidazoles and 1-substituted imidazoles for use in the treatment or prophylaxis of thrombo-embolic disorders | THE WELLCOME FOUNDATION LIMITED (GB) | 1979-03-07 | — | — | EP | disclosed |