SCHEMBL1105129

SCHEMBL1105129

NOS(=O)(=O)c1ccc2c(c1)nc1c3ccc4c5ccc6c7c(ccc(c8ccc(c(=O)n21)c3c84)c57)c(=O)n1c2ccc(S(=O)(=O)ON)cc2nc61

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 1/20 0.48
KMT2A Q03164 3/20 0.41
CYP1A2 P05177 2/20 0.41
NPC1 O15118 1/20 0.41
CYP3A4 P08684 1/20 0.41
RAB9A P51151 1/20 0.41
CAMKK1 Q8N5S9 2/20 0.40
CAMKK2 Q96RR4 2/20 0.40
MEN1 O00255 2/20 0.40
MAPT P10636 2/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C9 P11712 1/20 0.40
CASP1 P29466 1/20 0.40
CYP2C19 P33261 1/20 0.40
CASP7 P55210 1/20 0.40
AHR P35869 1/20 0.39
CSNK2A2 P19784 1/20 0.38
CSNK2B P67870 1/20 0.38
CSNK2A1 P68400 1/20 0.38
PIM3 Q86V86 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15255344 0.94 BCL2 (0.57) BCL2KMT2ACYP1A2NPC1CYP3A4
SCHEMBL15576744 0.93 BCL2 (0.58) BCL2KMT2ACYP1A2NPC1CYP3A4
SCHEMBL12036908 0.88 BCL2 (0.41) BCL2KMT2ACYP1A2NPC1CYP3A4
SCHEMBL15906200 0.84 BCL2 (0.48) BCL2KMT2ACYP1A2NPC1CYP3A4
SCHEMBL14300105 0.82 BCL2 (0.49) BCL2KMT2ACYP1A2NPC1CYP3A4
SCHEMBL18788923 0.81 BCL2 (0.46) BCL2KMT2ACYP1A2NPC1CYP3A4
SCHEMBL4070936 0.79 BCL2 (0.58) BCL2KMT2ACYP1A2NPC1CYP3A4
SCHEMBL20467118 0.78 BCL2 (0.42) BCL2KMT2ACYP1A2NPC1CYP3A4
SCHEMBL20033860 0.77 BCL2 (0.42) BCL2KMT2ACYP1A2NPC1CYP3A4
SCHEMBL12797089 0.76 AHR (0.63) BCL2KMT2ACYP1A2NPC1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8537304-B2 Liquid crystal display device and manufacturing method therefor HITACHI DISPLAYS, LTD. (JP) 2013-09-17 US disclosed
US-8237895-B2 Liquid crystal display device and method of manufacturing the same HITACHI DISPLAYS, LTD. (JP) 2012-08-07 US disclosed
US-8154693-B2 Liquid crystal display device and manufacturing method for same HITACHI DISPLAYS, LTD. (JP) 2012-04-10 US disclosed
US-20100289984-A1 LIQUID CRYSTAL DISPLAY DEVICE AND MANUFACTURING METHOD THEREFOR MAGNOLIA PURPLE CORPORATION (JP) 2010-11-18 US disclosed
US-20100002173-A1 Liquid Crystal Display Device and Manufacturing Method for Same IPS ALPHA SUPPORT CO., LTD. (JP) 2010-01-07 US disclosed
US-20090153781-A1 Liquid Crystal Display Device and Method of Manufacturing the Same IPS ALPHA SUPPORT CO., LTD. (JP) 2009-06-18 US disclosed