SCHEMBL15906200

SCHEMBL15906200

O=c1c2ccc3c4ccc5c(=O)n6c7ccc(S(=O)(=O)O)cc7nc6c6ccc(c7ccc(c2c37)c2nc3cc(S(=O)(=O)O)ccc3n12)c4c56

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 1/20 0.48
KMT2A Q03164 4/20 0.44
MEN1 O00255 3/20 0.44
CYP1A2 P05177 2/20 0.44
CAMKK1 Q8N5S9 2/20 0.44
CAMKK2 Q96RR4 2/20 0.44
MAPT P10636 2/20 0.44
CYP2C9 P11712 2/20 0.44
CYP2C19 P33261 2/20 0.44
CYP2D6 P10635 1/20 0.44
CASP1 P29466 1/20 0.44
CASP7 P55210 1/20 0.44
NPC1 O15118 1/20 0.44
CYP3A4 P08684 1/20 0.44
RAB9A P51151 1/20 0.44
CSNK2A2 P19784 1/20 0.42
CSNK2B P67870 1/20 0.42
CSNK2A1 P68400 1/20 0.42
PIM3 Q86V86 1/20 0.42
DYRK2 Q92630 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14300105 0.99 BCL2 (0.49) BCL2KMT2AMEN1CYP1A2CAMKK1
SCHEMBL4070936 0.94 BCL2 (0.58) BCL2KMT2AMEN1CYP1A2CAMKK1
SCHEMBL12882433 0.88 AHR (0.51) BCL2KMT2AMEN1CYP1A2CAMKK1
SCHEMBL12869050 0.88 AHR (0.51) BCL2KMT2AMEN1CYP1A2CAMKK1
SCHEMBL16180896 0.85 BCL2 (0.59) BCL2KMT2AMEN1CYP1A2CAMKK1
SCHEMBL14274371 0.85 BCL2 (0.39) BCL2KMT2AMEN1CYP1A2CAMKK1
SCHEMBL13203226 0.85 BCL2 (0.39) BCL2KMT2AMEN1CYP1A2CAMKK1
SCHEMBL1105129 0.84 BCL2 (0.48) BCL2KMT2AMEN1CYP1A2CAMKK1
SCHEMBL18788923 0.84 BCL2 (0.46) BCL2KMT2AMEN1CYP1A2CAMKK1
SCHEMBL14456967 0.83 AHR (0.47) BCL2KMT2AMEN1CYP1A2CAMKK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8790544-B2 Liquid-crystalline coating solution and polarizing film NITTO DENKO CORPORATION (JP) 2014-07-29 US disclosed