Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UPP1 | Q16831 | 5/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | HPGD | P15428 | 6/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11121714 | 0.86 | UPP1 (0.69) | UPP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL26354493 | 0.86 | UPP1 (0.51) | UPP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL29771552 | 0.82 | UPP1 (0.52) | UPP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6543058 | 0.81 | UPP1 (0.51) | UPP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL8901518 | 0.80 | UPP1 (0.61) | UPP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6625526 | 0.77 | UPP1 (0.66) | UPP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL5182348 | 0.76 | UPP1 (0.64) | UPP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL3794931 | 0.75 | KDM4E (0.64) | UPP1KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL6655303 | 0.75 | UPP1 (0.68) | UPP1KDM4EALDH1A1HPGDAPOBEC3G | |
| SCHEMBL8941878 | 0.73 | UPP1 (0.61) | UPP1KDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0159962-A2 | Fibre-reactive chromium or cobalt complexes, their preparation and their use | CIBA-GEIGY AG (CH) | 1985-10-30 | — | — | EP | disclosed |
| EP-0142104-A2 | Fibre-reactive chromium complexes, their preparation and their use | CIBA-GEIGY AG (CH) | 1985-05-22 | — | — | EP | disclosed |
| EP-0037377-A1 | Metal-complex dyestuffs, their preparation and use | CIBA-GEIGY AG (CH) | 1981-10-07 | — | — | EP | disclosed |
| EP-0009466-A1 | 1 : 2-Bis-chromium-complex dyestuffs from polyazo- or disazo-azomethine compounds, their preparation and their use | CIBA-GEIGY AG (CH) | 1980-04-02 | — | — | EP | disclosed |
| EP-0005207-A2 | Bis-1:2 chrome-disazo-bisazo methine dyestuffs, their preparation and use for dyeing of leather | CIBA-GEIGY AG (CH) | 1979-11-14 | — | — | EP | disclosed |