SCHEMBL11052116

CC(C)[C@H](N)C(=O)N[C@H](C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CC(N)=O)C(=O)O)C(C)C

nearest known ligand 0.56

Predicted protein targets (top 5)

	gene	UniProt	supporting neighbours	confidence
▸	BACE1	P56817	18/20	0.56

▸	CTSD	P07339	4/20	0.54

▸	BACE2	Q9Y5Z0	1/20	0.45

▸	ECE1	P42892	1/20	0.44

▸	ENPEP	Q07075	1/20	0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL11052122	0.94	BACE1 (0.50)	BACE1CTSDECE1
SCHEMBL11049992	0.94	BACE1 (0.60)	BACE1CTSDECE1ENPEP
SCHEMBL30974202	0.90	BACE1 (0.46)	BACE1CTSDENPEP
SCHEMBL30587028	0.89	BACE1 (0.54)	BACE1CTSDECE1ENPEP
SCHEMBL11050000	0.88	BACE1 (0.54)	BACE1CTSDECE1
SCHEMBL29482772	0.88	BACE1 (0.60)	BACE1CTSDBACE2
SCHEMBL30269676	0.87	ENPEP (0.47)	BACE1CTSDBACE2ENPEP
SCHEMBL29370769	0.87	ENPEP (0.46)	BACE1CTSDBACE2ENPEP
SCHEMBL29630420	0.86	BACE1 (0.52)	BACE1CTSD
SCHEMBL30193504	0.86	BACE1 (0.52)	BACE1CTSDECE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
US-4426324-A	Immunopotentiating peptides	HOFFMANN-LA ROCHE INC. (US)	1984-01-17	—	—	US	disclosed