SCHEMBL11052170

SCHEMBL11052170

CCOC(=O)NN=C(c1ccc(Cl)cc1)c1ccc(NC(=O)OCC)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.59
KMT2A Q03164 6/20 0.52
ALDH1A1 P00352 4/20 0.52
SMN1; SMN2 Q16637 5/20 0.51
CYP19A1 P11511 1/20 0.48
MAPT P10636 4/20 0.47
RAB9A P51151 2/20 0.47
NPC1 O15118 1/20 0.47
HPGD P15428 1/20 0.47
CRHBP P24387 1/20 0.47
CRHR2 Q13324 1/20 0.47
MEN1 O00255 5/20 0.46
HTT P42858 2/20 0.46
ALOX12 P18054 1/20 0.46
NPSR1 Q6W5P4 3/20 0.46
LMNA P02545 2/20 0.45
POLB P06746 1/20 0.45
GAA P10253 2/20 0.45
CHRM2 P08172 1/20 0.44
CHRM4 P08173 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10971917 0.86 SMN1; SMN2 (0.57) L3MBTL1KMT2AALDH1A1SMN1; SMN2MAPT
SCHEMBL1187952 0.84 L3MBTL1 (0.77) L3MBTL1KMT2AALDH1A1SMN1; SMN2CYP19A1
SCHEMBL11047592 0.83 L3MBTL1 (0.68) L3MBTL1KMT2AALDH1A1SMN1; SMN2CYP19A1
SCHEMBL8007278 0.81 SMN1; SMN2 (0.48) L3MBTL1KMT2AALDH1A1SMN1; SMN2MAPT
SCHEMBL14359273 0.81 SMN1; SMN2 (0.48) L3MBTL1KMT2AALDH1A1SMN1; SMN2MAPT
SCHEMBL8395979 0.81 SMN1; SMN2 (0.48) L3MBTL1KMT2ASMN1; SMN2MAPTHPGD
SCHEMBL11327733 0.81 SMN1; SMN2 (0.48) L3MBTL1KMT2AALDH1A1SMN1; SMN2MAPT
SCHEMBL7995488 0.80 SMN1; SMN2 (0.47) KMT2AALDH1A1SMN1; SMN2MAPTRAB9A
SCHEMBL11096987 0.80 SMN1; SMN2 (0.47) L3MBTL1KMT2AALDH1A1SMN1; SMN2MAPT
SCHEMBL14359275 0.80 SMN1; SMN2 (0.47) L3MBTL1KMT2AALDH1A1SMN1; SMN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4432994-A SUBSTITUTED BENZOPHENONE HYDRAZONES AS INSECTICIDES, MITICIDES THE BOOTS COMPANY (GB) 1984-02-21 US disclosed
US-4331680-A SUBSTITUTED BENZOPHENONE HYDRAZONE, INSECTICIDES THE BOOTS COMPANY (GB) 1982-05-25 US disclosed
EP-0026040-A1 Substituted benzophenone hydrazones, pesticidal compositions containing them and method of combating pests FBC LIMITED (GB) 1981-04-01 EP disclosed