Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | VCP | P55072 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.41 |
| ▸ | EP300 | Q09472 | 8/20 | 0.40 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1105204 | 0.89 | EP300 (0.39) | FGFR1SLC22A6ALDH1A1LMNANFKB1 | |
| SCHEMBL1105226 | 0.85 | FGFR1 (0.53) | FGFR1SLC22A6ALDH1A1LMNANFKB1 | |
| SCHEMBL14509990 | 0.84 | FGFR1 (0.44) | FGFR1SLC22A6ALDH1A1LMNANFKB1 | |
| SCHEMBL1135883 | 0.84 | FGFR1 (0.44) | FGFR1SLC22A6ALDH1A1LMNANFKB1 | |
| SCHEMBL13379601 | 0.84 | ALDH1A1 (0.48) | FGFR1SLC22A6ALDH1A1LMNANFKB1 | |
| SCHEMBL1095071 | 0.83 | FGFR1 (0.67) | FGFR1SLC22A6ALDH1A1LMNANFKB1 | |
| SCHEMBL1095404 | 0.83 | FGFR1 (0.67) | FGFR1SLC22A6ALDH1A1LMNANFKB1 | |
| SCHEMBL9666275 | 0.83 | BLM (0.55) | FGFR1SLC22A6ALDH1A1LMNANFKB1 | |
| SCHEMBL1096324 | 0.81 | FGFR1 (0.49) | FGFR1SLC22A6ALDH1A1LMNANFKB1 | |
| SCHEMBL15046004 | 0.78 | FGFR1 (0.71) | FGFR1SLC22A6ALDH1A1LMNANFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8153787-B2 | Azacytosine derivatives useful as antiviral agents | K.U. LEUVEN RESEARCH & DEVELOPMENT (BE) | 2012-04-10 | — | — | US | disclosed |
| US-20090005346-A1 | Azacytosine Derivatives Useful as Antiviral Agents | K.U.LEUVEN RESEARCH & DEVELOPMENT (BE) | 2009-01-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090005346-A1 | Azacytosine Derivatives Useful as Antiviral Agents | ITPA, ZC3HAV1, MTAP | FGFR1 4874/4885SLC22A6 2692/4885ALDH1A1 1877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.