Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11476946 | 0.87 | ALDH1A1 (0.60) | ALDH1A1NPC1L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL7602428 | 0.83 | TSHR (0.40) | ALDH1A1NPC1L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL20207415 | 0.83 | TSHR (0.40) | ALDH1A1NPC1L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL11208914 | 0.82 | ALDH1A1 (0.41) | ALDH1A1NPC1L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL11050725 | 0.80 | ALDH1A1 (0.49) | ALDH1A1NPC1L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL10422905 | 0.79 | ALDH1A1 (0.48) | ALDH1A1NPC1L3MBTL1SMN1; SMN2RAB9A | |
| SCHEMBL22620083 | 0.79 | ALDH1A1 (0.41) | ALDH1A1NPC1SMN1; SMN2RAB9AHTT | |
| SCHEMBL11054024 | 0.79 | ALDH1A1 (0.44) | ALDH1A1NPC1SMN1; SMN2RAB9AHTT | |
| SCHEMBL809584 | 0.79 | PPARG (0.39) | ALDH1A1HTTTSHRUSP2HSD17B10 | |
| SCHEMBL11057392 | 0.79 | ALDH1A1 (0.43) | ALDH1A1NPC1L3MBTL1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4439380-A | Photopolymerizable composition, especially for dental purposes | ETABLISSEMENT DENTAIRE IVOCLAR (LI) | 1984-03-27 | — | — | US | claimed |
| US-4439380-A | Photopolymerizable composition, especially for dental purposes | ETABLISSEMENT DENTAIRE IVOCLAR (LI) | 1984-03-27 | — | — | US | disclosed |