SCHEMBL11052262

SCHEMBL11052262

C=CCSSSP(=O)(O)O

nearest known ligand 0.52

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.52
ALDH1A1 P00352 2/20 0.52
CYP3A4 P08684 2/20 0.52
HPGD P15428 2/20 0.52
ALOX15 P16050 1/20 0.43
ALOX5 P09917 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
PTGS2 P35354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Diallyldisulfide SCHEMBL31552427 0.78 TRPA1 (0.65) TRPA1ALDH1A1CYP3A4HPGDALOX15
SCHEMBL11052255 0.73
Allitridin SCHEMBL28776713 0.71 TRPA1 (1.00) TRPA1ALDH1A1CYP3A4HPGDALOX15
Allitridin SCHEMBL562845 0.71
Diallyl Tetrasulfide SCHEMBL389609 0.71 TRPA1 (0.86) TRPA1ALDH1A1CYP3A4HPGDALOX15
SCHEMBL1993851 0.70
Hydrochloric Acid SCHEMBL8958915 0.69
SCHEMBL392677 0.68 TRPA1 (0.80) TRPA1ALDH1A1CYP3A4HPGDALOX15
SCHEMBL389755 0.68 TRPA1 (0.80) TRPA1ALDH1A1CYP3A4HPGDALOX15
SCHEMBL2987869 0.68 TRPA1 (0.80) TRPA1ALDH1A1CYP3A4HPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0042661-B1 SCORCH-SAFE ACCELERATION OF URETHANE VULCANIZATION OF UNSATURATED RUBBERS UNIROYAL, INC. (US) 1985-08-07 EP claimed
US-4324870-A ADDUCT OF NITROSOPHENOL AND METHYLENEBIS/4-PHENYL ISOCYANATE/, DITHIOPHOSPHORIC ACID ESTER CURING AGENT UNIROYAL, INC. (US) 1982-04-13 US claimed
EP-0042661-A1 Scorch-safe acceleration of urethane vulcanization of unsaturated rubbers UNIROYAL, INC. (US) 1981-12-30 EP claimed
EP-0042661-B1 SCORCH-SAFE ACCELERATION OF URETHANE VULCANIZATION OF UNSATURATED RUBBERS UNIROYAL, INC. (US) 1985-08-07 EP disclosed
US-4324870-A ADDUCT OF NITROSOPHENOL AND METHYLENEBIS/4-PHENYL ISOCYANATE/, DITHIOPHOSPHORIC ACID ESTER CURING AGENT UNIROYAL, INC. (US) 1982-04-13 US disclosed
EP-0042661-A1 Scorch-safe acceleration of urethane vulcanization of unsaturated rubbers UNIROYAL, INC. (US) 1981-12-30 EP disclosed