Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.61 |
| ▸ | TSHR | P16473 | 2/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.61 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.54 |
| ▸ | UGT2B7 | P16662 | 7/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.41 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.36 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9880617 | 1.00 | ALDH1A1 (0.61) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL31139943 | 1.00 | ALDH1A1 (0.61) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL8611875 | 1.00 | ALDH1A1 (0.61) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL3112008 | 1.00 | ALDH1A1 (0.61) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL3112011 | 1.00 | ALDH1A1 (0.61) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL19958385 | 0.87 | ALDH1A1 (0.61) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL27017541 | 0.87 | ALDH1A1 (0.61) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL385019 | 0.87 | ALDH1A1 (0.57) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL10101191 | 0.87 | ALDH1A1 (0.57) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 | |
| SCHEMBL9880760 | 0.87 | ALDH1A1 (0.57) | ALDH1A1CYP3A4CYP2C9TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 471 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2471939-B1 | Method for producing 1-(2-hydroxyethyl) 2,5,5,8a-tetramethyldecahydronaphthalene-2-ol by microbial fermentation | KAO CORP (JP) | 2020-11-04 | — | — | EP | claimed |
| EP-1997879-B1 | MICROORGANISM AND METHOD FOR PRODUCING DECAHYDRO-2-HYDROXY-2,5,5,8a-TETRAMETHYLNAPHTHALENEETHANOL AND/OR SCLAREOLIDE (DECAHYDRO-3a,6,6,9a- TETRAMETHYLNAPHTHO[2,1-b]FURAN-2(1H)-ONE) USING THE SAME | KAO CORP (JP) | 2015-07-01 | — | — | EP | claimed |
| US-8822186-B2 | Method for producing microbial fermentation product | KAO CORPORATION (JP) | 2014-09-02 | — | — | US | claimed |
| EP-2400025-B1 | Process for producing microbial fermentation product | KAO CORP (JP) | 2013-11-20 | — | — | EP | claimed |
| EP-2123765-B1 | Method for production of microbial fermentation product | KAO CORP (JP) | 2013-07-31 | — | — | EP | claimed |
| US-8293518-B2 | Microorganism and method for producing dodecahydro-3a,6,6,9a-tetramethylnaphtho[2,1-b]furan intermediate using the novel microorganism | KAO CORPORATION (JP) | 2012-10-23 | — | — | US | claimed |
| US-8252565-B2 | Method for production of microbial fermentation product | KAO CORPORATION (JP) | 2012-08-28 | — | — | US | claimed |
| EP-2471939-A1 | METHOD FOR PRODUCING MICROBIAL FERMENTATION PRODUCT | Kao Corporation (JP) | 2012-07-04 | — | — | EP | claimed |
| US-20120135484-A1 | METHOD FOR PRODUCING MICROBIAL FERMENTATION PRODUCT | KAO CORPORATION (JP) | 2012-05-31 | — | — | US | claimed |
| US-20120107917-A1 | Novel Microorganism and Method for Producing Dodecahydro-3a,6,6,9a-Tetramethylnaphtho[2,1-b]Furan Intermediate Using the Novel Microorganism | KAO CORPORATION (JP) | 2012-05-03 | — | — | US | claimed |
| EP-0550889-A1 | Process for producing L-Ambrox | KURARAY CO., LTD. (JP) | 1993-07-14 | — | — | EP | claimed |
| US-5136112-A | PROCESS FOR PREPARING 2-HYDROXY-2 5, 5, 9-TETRAMETHYLDECALYL ETHANOL | KAO CORPORATION (JP) | 1992-08-04 | — | — | US | claimed |
| EP-0471281-A1 | Process for preparing 2-hydroxy-2, 5, 5, 9-tetramethyldecalyl ethanol | KAO CORPORATION (JP) | 1992-02-19 | — | — | EP | claimed |
| EP-0170955-B1 | Process for the preparation of (+/-)-3a-6,6,9a-tetramethylperhydronaphto[2,1-b]furan | FIRMENICH SA (CH) | 1992-01-08 | — | — | EP | claimed |
| US-4613710-A | CYCLIZATION OF 1B-(2-HYDROXYETHYL)-PERHYDRO-2,5,5,82B-TETRAMETHYL-2B-TRANS-NAPHTHALENOL | FIRMENICH SA (CH) | 1986-09-23 | — | — | US | claimed |
| EP-0170955-A2 | Process for the preparation of (+/-)-3a-6,6,9a-tetramethylperhydronaphto[2,1-b]furan | FIRMENICH SA (CH) | 1986-02-12 | — | — | EP | claimed |
| EP-0165458-A2 | (+)-Ambrox, process for production thereof and use thereof | T. HASEGAWA COMPANY, LTD. (JP) | 1985-12-27 | — | — | EP | claimed |
| US-4207905-A | Isobutyl substituted heterocyclic compounds for augmenting or enhancing the organoleptic properties of smoking tobaccos and smoking tobacco articles | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1980-06-17 | — | — | US | claimed |
| US-4170236-A | TRIISOBUTYL TRIOXANE | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1979-10-09 | — | — | US | claimed |
| US-4135520-A | CIGARETTES | INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) | 1979-01-23 | — | — | US | claimed |