⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16630493 | 0.74 | — | — | |
| SCHEMBL9461216 | 0.74 | — | — | |
| SCHEMBL2437457 | 0.69 | — | — | |
| SCHEMBL9781712 | 0.64 | — | — | |
| SCHEMBL11201569 | 0.63 | — | — | |
| SCHEMBL873622 | 0.62 | — | — | |
| SCHEMBL2210464 | 0.61 | GAA (0.33) | — | |
| SCHEMBL28029196 | 0.61 | L3MBTL1 (0.34) | — | |
| Formamide SCHEMBL27805837 | 0.61 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL7492745 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4438277-A | Hydronaphthalene derivatives | SANKYO COMPANY, LIMITED (JP) | 1984-03-20 | — | — | US | disclosed |
| US-4361515-A | Antihyperlipemic dihydro-ML-236B derivatives, their preparation and use | SANKYO COMPANY, LIMITED (JP) | 1982-11-30 | — | — | US | disclosed |