Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 1/20 | 0.56 |
| ▸ | DRD1 | P21728 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.46 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11052355 | 0.86 | DRD2 (0.64) | DRD2DRD1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL8764580 | 0.85 | DRD2 (0.55) | DRD2DRD1BCHEACHETBXA2R | |
| SCHEMBL20170872 | 0.85 | DRD2 (0.55) | DRD2DRD1BCHEACHETBXA2R | |
| SCHEMBL8765230 | 0.85 | DRD2 (0.55) | DRD2DRD1BCHEACHETBXA2R | |
| SCHEMBL11057207 | 0.79 | DRD2 (0.69) | DRD2DRD1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL21131708 | 0.77 | DRD2 (0.76) | DRD2DRD1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL11056682 | 0.76 | DRD2 (0.70) | DRD2DRD1KDM4EBCHEACHE | |
| SCHEMBL11051922 | 0.74 | DRD2 (0.54) | DRD2DRD1BCHEACHETBXA2R | |
| SCHEMBL11055690 | 0.74 | DRD2 (0.71) | DRD2DRD1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL8741289 | 0.72 | DRD2 (0.43) | DRD2DRD1KDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4461895-A | FOR COMBATTING COLDS AND ALLERGIES | WARNER-LAMBERT COMPANY (US) | 1984-07-24 | — | — | US | disclosed |
| EP-0064685-A1 | Dibenzo(de,g)quinolines, processes for their preparation and pharmaceutical preparations containing them | GÖDECKE AKTIENGESELLSCHAFT (DE) | 1982-11-17 | — | — | EP | disclosed |