Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | NPEPPS | P55786 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.60 |
| ▸ | ANPEP | P15144 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | RAB9A | P51151 | 1/20 | 0.59 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.59 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.49 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10888188 | 0.87 | ADORA2A (0.46) | SMN1; SMN2NPEPPSTP53CYP3A4ANPEP | |
| Hydrochloric Acid SCHEMBL11057140 | 0.86 | SMN1; SMN2 (0.67) | SMN1; SMN2NPEPPSTP53CYP3A4ANPEP | |
| SCHEMBL10885822 | 0.83 | ADORA2A (0.46) | SMN1; SMN2NPEPPSTP53CYP3A4ANPEP | |
| SCHEMBL10886560 | 0.83 | ADORA2A (0.49) | SMN1; SMN2NPEPPSTP53CYP3A4ANPEP | |
| SCHEMBL11198593 | 0.82 | SMN1; SMN2 (0.66) | SMN1; SMN2NPEPPSTP53CYP3A4ANPEP | |
| SCHEMBL10886296 | 0.82 | SMN1; SMN2 (0.66) | SMN1; SMN2NPEPPSTP53CYP3A4ANPEP | |
| Water SCHEMBL11057575 | 0.82 | SMN1; SMN2 (0.65) | SMN1; SMN2NPEPPSTP53CYP3A4ANPEP | |
| Hydrochloric Acid SCHEMBL11200420 | 0.81 | SMN1; SMN2 (0.66) | SMN1; SMN2NPEPPSTP53CYP3A4ANPEP | |
| Hydrochloric Acid SCHEMBL10889749 | 0.81 | SMN1; SMN2 (0.66) | SMN1; SMN2NPEPPSTP53CYP3A4ANPEP | |
| Hydrochloric Acid SCHEMBL10888079 | 0.81 | SMN1; SMN2 (0.66) | SMN1; SMN2NPEPPSTP53CYP3A4ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479942-A | Tetrahydrofurnancarboxylic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-30 | — | — | US | disclosed |
| EP-0071926-A1 | New ribofuranuronic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-02-16 | — | — | EP | disclosed |