Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 6/20 | 0.46 |
| ▸ | ADORA2B | P29275 | 6/20 | 0.46 |
| ▸ | AHCY | P23526 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | NPEPPS | P55786 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ANPEP | P15144 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10886574 | 0.96 | ADORA2A (0.49) | ADORA2AADORA2BAHCYSMN1; SMN2NPEPPS | |
| SCHEMBL11060622 | 0.93 | ADORA2A (0.45) | ADORA2AADORA2BSMN1; SMN2NPEPPSTP53 | |
| SCHEMBL10883897 | 0.91 | ADORA2A (0.48) | ADORA2AADORA2BAHCYNPEPPS | |
| SCHEMBL10887386 | 0.91 | ADORA2A (0.52) | ADORA2AADORA2BAHCYNPEPPS | |
| SCHEMBL10885276 | 0.91 | ADORA2A (0.52) | ADORA2AADORA2BAHCYNPEPPS | |
| SCHEMBL10885962 | 0.88 | ADORA2A (0.46) | ADORA2AADORA2BAHCYSMN1; SMN2NPEPPS | |
| SCHEMBL10884643 | 0.85 | AHCY (0.59) | AHCYSMN1; SMN2NPEPPSTP53CYP3A4 | |
| SCHEMBL10885229 | 0.85 | ADORA2A (0.52) | ADORA2AADORA2BAHCY | |
| SCHEMBL11054046 | 0.83 | SMN1; SMN2 (0.60) | ADORA2AADORA2BSMN1; SMN2NPEPPSTP53 | |
| SCHEMBL10896379 | 0.83 | AHCY (0.54) | AHCYSMN1; SMN2NPEPPSTP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0071926-B1 | NEW RIBOFURANURONIC ACID DERIVATIVES, PROCESSES FOR PREPARATION THEREOF AND PHARMACEUTICAL COMPOSITIONS THEREOF | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-10-08 | — | — | EP | disclosed |
| US-4479942-A | Tetrahydrofurnancarboxylic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1984-10-30 | — | — | US | disclosed |
| EP-0071926-A1 | New ribofuranuronic acid derivatives, processes for preparation thereof and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-02-16 | — | — | EP | disclosed |