Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 9/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.37 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11053748 | 0.70 | HDAC1 (0.62) | HDAC1HDAC6HDAC8HDAC2 | |
| SCHEMBL9313535 | 0.69 | RECQL (0.33) | — | |
| SCHEMBL11052430 | 0.68 | HDAC6 (0.52) | HDAC1HDAC6HDAC8MEP1BHDAC10 | |
| Dopamine SCHEMBL28841647 | 0.65 | KDM4E (0.60) | HDAC1HDAC6 | |
| SCHEMBL3054693 | 0.64 | HDAC8 (0.41) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL11054512 | 0.64 | TRPV1 (0.62) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL7808011 | 0.64 | HDAC2 (0.44) | HDAC1HDAC6HDAC8HDAC2HDAC3 | |
| SCHEMBL11055371 | 0.64 | KMT2A (0.42) | HDAC1HDAC6HDAC8MEP1B | |
| SCHEMBL15103343 | 0.64 | ALOX5 (0.73) | — | |
| SCHEMBL3962866 | 0.64 | SELL (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4448730-A | ANTITUMOR AGENTS | RIET BARTHOLOMEUS VAN T | 1984-05-15 | — | — | US | disclosed |