SCHEMBL11054288

SCHEMBL11054288

Cc1ccc(C(C)C(=O)O)c2ccccc12

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.48
PTGS2 P35354 4/20 0.43
PTGS1 P23219 2/20 0.41
POLB P06746 1/20 0.41
CXCL8 P10145 1/20 0.40
MMP1 P03956 1/20 0.40
MMP2 P08253 1/20 0.40
MMP9 P14780 1/20 0.40
MMP8 P22894 1/20 0.40
MMP12 P39900 1/20 0.40
MMP13 P45452 1/20 0.40
MMP14 P50281 1/20 0.40
MMP16 P51512 1/20 0.40
AKR1B1 P15121 1/20 0.40
ALDH1A1 P00352 2/20 0.39
HPGD P15428 2/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
MAPK1 P28482 1/20 0.39
PRNP P04156 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17491866 0.90 PTGS2 (0.50) PTGS2PTGS1POLBCXCL8MMP1
SCHEMBL19145987 0.89 CYP1A2 (0.48) CYP1A2PTGS2POLBALDH1A1HPGD
SCHEMBL27851962 0.87 CYP1A2 (0.50) CYP1A2ALDH1A1MAPTKDM4ECYP2A6
SCHEMBL28816574 0.81 CYP1A2 (0.43) CYP1A2ALDH1A1HPGDLMNAMAPT
SCHEMBL11054382 0.81 TSHR (0.50) CYP1A2POLBMMP8ALDH1A1HPGD
SCHEMBL9352289 0.80 CYP1A2 (0.42) CYP1A2PTGS2PTGS1ALDH1A1LMNA
SCHEMBL11793136 0.77 PTGS1 (0.56) PTGS2PTGS1HPGDMAPT
SCHEMBL11460736 0.76 AKR1B1 (0.53) CYP1A2PTGS2PTGS1POLBAKR1B1
SCHEMBL12061479 0.76 CYP1A2 (0.56) CYP1A2ALDH1A1LMNAMAPTKDM4E
SCHEMBL30717242 0.76 PTGS2 (0.48) PTGS2PTGS1CXCL8MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4436715-A Storage and retrieval of singlet oxygen KMS FUSION, INC. (US) 1984-03-13 US disclosed