⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14764661 | 0.75 | ALDH1A1 (0.42) | — | |
| SCHEMBL13424122 | 0.74 | — | — | |
| SCHEMBL3225029 | 0.74 | — | — | |
| SCHEMBL23047662 | 0.74 | ALDH1A1 (0.33) | — | |
| SCHEMBL11019759 | 0.72 | ALDH1A1 (0.44) | — | |
| SCHEMBL14141054 | 0.72 | — | — | |
| SCHEMBL16421032 | 0.72 | — | — | |
| SCHEMBL11094107 | 0.71 | ALDH1A1 (0.39) | — | |
| SCHEMBL11055439 | 0.71 | ALDH1A1 (0.39) | — | |
| SCHEMBL11055421 | 0.71 | ALDH1A1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2753702-B1 | CELL-FREE PREPARATION OF CARBAPENEMS | GREENLIGHT BIOSCIENCES INC (US) | 2021-12-15 | — | — | EP | disclosed |
| US-20170096692-A1 | CELL-FREE PREPARATION OF CARBAPENEMS | GREENLIGHT BIOSCIENCES, INC. (US) | 2017-04-06 | — | — | US | disclosed |
| US-9469861-B2 | Cell-free preparation of carbapenems | GREENLIGHT BIOSCIENCES, INC. (US) | 2016-10-18 | — | — | US | disclosed |
| US-20130065878-A1 | CELL-FREE PREPARATION OF CARBAPENEMS | GREENLIGHT BIOSCIENCES, INC. | 2013-03-14 | — | — | US | disclosed |
| WO-2013036787-A2 | CELL-FREE PREPARATION OF CARBAPENEMS | GREENLIGHT BIOSCIENCES, INC. (US) | 2013-03-14 | — | — | WO | disclosed |
| EP-0008497-B1 | BETA-LACTAM-CONTAINING COMPOUNDS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | BEECHAM GROUP PLC (GB) | 1984-10-24 | — | — | EP | disclosed |
| US-4446146-A | β-Lactam containing compounds, their preparation and use | BEECHAM GROUP LIMITED (GB) | 1984-05-01 | — | — | US | disclosed |
| EP-0038087-A2 | Beta-lactam containing compounds, their preparation and use | BEECHAM GROUP PLC (GB) | 1981-10-21 | — | — | EP | disclosed |
| EP-0008497-A1 | Beta-lactam-containing compounds, their preparation and pharmaceutical compositions containing them | BEECHAM GROUP PLC (GB) | 1980-03-05 | — | — | EP | disclosed |