Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B2 | P37059 | 1/20 | 0.58 |
| ▸ | CDC25B | P30305 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA7 | P43166 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.49 |
| ▸ | CDC25A | P30304 | 1/20 | 0.48 |
| ▸ | CDC25C | P30307 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11051219 | 0.82 | CA12 (0.59) | HSD17B2CDC25BMAPTRAB9AKDM4E | |
| SCHEMBL15788487 | 0.81 | CDC25B (0.52) | HSD17B2CDC25BMAPTRAB9AKDM4E | |
| SCHEMBL10391503 | 0.81 | CDC25B (0.56) | CDC25BMAPTRAB9AKDM4EMEN1 | |
| SCHEMBL11052006 | 0.81 | ALDH1A1 (0.55) | CDC25BMAPTRAB9AKDM4ENPC1 | |
| SCHEMBL30676976 | 0.80 | ALDH1A1 (0.56) | MAPTRAB9AKDM4ENPC1MEN1 | |
| SCHEMBL4404905 | 0.80 | ALDH1A1 (0.56) | MAPTRAB9AKDM4ENPC1MEN1 | |
| SCHEMBL2671487 | 0.80 | KDM4E (0.62) | CDC25BRAB9AKDM4ENPC1MEN1 | |
| SCHEMBL10484070 | 0.79 | KMT2A (0.59) | CDC25BMAPTRAB9AKDM4ENPC1 | |
| SCHEMBL5680100 | 0.79 | HSD17B2 (0.65) | HSD17B2MAPTRAB9AKDM4ENPC1 | |
| SCHEMBL19216873 | 0.79 | CDC25B (0.50) | HSD17B2CDC25BMAPTRAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4490370-A | BACTERICIDES | ELI LILLY AND COMPANY (US) | 1984-12-25 | — | — | US | disclosed |
| EP-0122155-A2 | Improvements in or relating to naphthylglycyl cephalosporin derivatives | ELI LILLY AND COMPANY (US) | 1984-10-17 | — | — | EP | disclosed |