Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13956776 | 0.91 | CYP2C9 (0.71) | CYP2C9LMNACYP2C19KMT2AALDH1A1 | |
| SCHEMBL11814565 | 0.78 | PPID (0.48) | CYP2C9LMNATGM2CYP2C19KMT2A | |
| SCHEMBL5175031 | 0.78 | CYP2C9 (0.77) | CYP2C9LMNACYP2C19KMT2AALDH1A1 | |
| SCHEMBL10157129 | 0.77 | MEN1 (0.59) | CYP2C9LMNACYP2C19KMT2AALDH1A1 | |
| SCHEMBL10157126 | 0.77 | HPGD (0.56) | CYP2C9LMNAKMT2AALDH1A1POLB | |
| SCHEMBL5358931 | 0.76 | CYP2C9 (0.75) | CYP2C9LMNACYP2C19KMT2AALDH1A1 | |
| SCHEMBL7672594 | 0.76 | CYP2C9 (0.75) | CYP2C9LMNACYP2C19KMT2AALDH1A1 | |
| SCHEMBL11049989 | 0.74 | ALDH1A1 (0.40) | CYP2C9LMNAALDH1A1POLBMAPT | |
| SCHEMBL17845078 | 0.74 | CYP2C9 (0.73) | CYP2C9LMNACYP2C19KMT2AALDH1A1 | |
| SCHEMBL7930854 | 0.74 | ALDH1A1 (0.59) | CYP2C9LMNATGM2CYP2C19KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4161580-A | Thermosetting mixtures of polyimide beta-amino crotonic acid derivative and polyamine which are stable on storage | CIBA-GEIGY CORPORATION (US) | 1979-07-17 | — | — | US | claimed |
| US-4089845-A | Thermosetting mixtures which are stable on storage from polyimide and .beta. | CIBA-GEIGY CORPORATION (US) | 1978-05-16 | — | — | US | claimed |
| US-4424336-A | Meat-curable mixture, which are stable on storage, of epoxide resin, 3-aminocrotonic acid derivatives and maleimide compound | CIBA-GEIGY CORPORATION (US) | 1984-01-03 | — | — | US | disclosed |
| US-4360655-A | Heat-curable mixtures, which are stable on storage, of epoxide compounds β-aminocrotonic acid derivatives and polyamine | CIBA-GEIGY CORPORATION (US) | 1982-11-23 | — | — | US | disclosed |
| US-4348511-A | POLYURETHANES MODIFIED WITH BETA-AMINOCROTONIC ACID DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1982-09-07 | — | — | US | disclosed |
| US-4291146-A | Heat-curable mixtures, which are stable on storage, of expoxide resins and β-aminocrotonic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1981-09-22 | — | — | US | disclosed |
| US-4284752-A | Process for producing crosslinked unsaturated polymers by reaction of .beta. | CIBA-GEIGY CORPORATION (US) | 1981-08-18 | — | — | US | disclosed |
| US-4161580-A | Thermosetting mixtures of polyimide beta-amino crotonic acid derivative and polyamine which are stable on storage | CIBA-GEIGY CORPORATION (US) | 1979-07-17 | — | — | US | disclosed |
| US-4089845-A | Thermosetting mixtures which are stable on storage from polyimide and .beta. | CIBA-GEIGY CORPORATION (US) | 1978-05-16 | — | — | US | disclosed |