Toluene

Toluene

SCHEMBL11054867

CC1(O)C=CC=CC1.Cc1ccccc1

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.41
TSHR P16473 1/20 0.41
ALOX12 P18054 1/20 0.41
ACHE P22303 1/20 0.41
OPRM1 P35372 2/20 0.33
OPRK1 P41145 2/20 0.33
OPRL1 P41146 2/20 0.33
CES2 O00748 1/20 0.31
CES1 P23141 1/20 0.31
OPRD1 P41143 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9772276 0.82
Anisole SCHEMBL27862557 0.81 CA4 (0.47) LMNATSHROPRM1OPRK1OPRL1
Acetone SCHEMBL27850981 0.74 CYP3A4 (0.31)
Toluene SCHEMBL27528875 0.68 ACHE (0.61) LMNATSHRALOX12ACHECES2
Toluene SCHEMBL27277200 0.68 ACHE (0.61) LMNATSHRALOX12ACHECES2
Phenol SCHEMBL28448774 0.68 CA12 (0.42)
Toluene SCHEMBL23491537 0.67 ACHE (0.79) LMNATSHRALOX12ACHECES2
Cyclooctane SCHEMBL16909938 0.67 ACHE (0.79) LMNATSHRALOX12ACHECES2
Toluene SCHEMBL598534 0.67 ACHE (0.79) LMNATSHRALOX12ACHECES2
Toluene SCHEMBL11529127 0.67 ACHE (0.79) LMNATSHRALOX12ACHECES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4468446-A Electrostatographic encapsulated toner material improved in powder characteristics FUJI PHOTO FILM CO., LTD. (JP) 1984-08-28 US disclosed