SCHEMBL11054964

SCHEMBL11054964

Cc1c(O)c(O)c(O)c(C)c1F

nearest known ligand 0.32

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
NUAK1 O60285 1/20 0.30
IGF1R P08069 1/20 0.30
MET P08581 1/20 0.30
PIM1 P11309 1/20 0.30
SRC P12931 1/20 0.30
AXL P30530 1/20 0.30
AKT1 P31749 1/20 0.30
KDR P35968 1/20 0.30
NEK2 P51955 1/20 0.30
PLK1 P53350 1/20 0.30
PTK2 Q05397 1/20 0.30
PKN1 Q16512 1/20 0.30
AURKB Q96GD4 1/20 0.30
NEK6 Q9HC98 1/20 0.30
ALK Q9UM73 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5589298 0.89 TAS1R3 (0.30)
SCHEMBL9801129 0.80 TAS1R3 (0.31)
SCHEMBL7559713 0.76 IGF1R (0.35) NUAK1IGF1RMETPIM1SRC
SCHEMBL13199249 0.76 IGF1R (0.35) NUAK1IGF1RMETPIM1SRC
SCHEMBL23848680 0.76 TAS1R3 (0.32)
SCHEMBL265076 0.76
SCHEMBL26563459 0.74 KDM4E (0.31)
SCHEMBL5588804 0.73
SCHEMBL5588775 0.73
SCHEMBL15676352 0.72 IGF1R (0.33) NUAK1IGF1RMETPIM1SRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4436804-A Light-sensitive polymeric diazonium condensates and reproduction compositions and materials therewith AMERICAN HOECHST CORPORATION (US) 1984-03-13 US disclosed