SCHEMBL11054974

SCHEMBL11054974

O=C(O)Oc1ccc(OOc2ccc(OC(=O)O)cc2)cc1

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.46
ELANE P08246 9/20 0.45
HSD17B10 Q99714 3/20 0.43
RAB9A P51151 1/20 0.42
MAPT P10636 3/20 0.42
ALDH1A1 P00352 2/20 0.42
HSP90AA1 P07900 1/20 0.42
GAA P10253 1/20 0.42
POLB P06746 1/20 0.41
PKM P14618 1/20 0.41
KMT2A Q03164 3/20 0.38
HTT P42858 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MEN1 O00255 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL465132 0.91 LMNA (0.52) LMNAELANEHSD17B10RAB9AMAPT
SCHEMBL28670578 0.88 LMNA (0.50) LMNAELANEHSD17B10RAB9AMAPT
SCHEMBL2637327 0.83 HSD17B10 (0.59) LMNAELANEHSD17B10RAB9AMAPT
SCHEMBL194962 0.83 HSD17B10 (0.59) LMNAELANEHSD17B10RAB9AMAPT
SCHEMBL18417 0.83 ELANE (0.54) LMNAELANEHSD17B10RAB9AMAPT
SCHEMBL24435576 0.81 LMNA (0.70) LMNAELANEHSD17B10RAB9AMAPT
SCHEMBL308379 0.81 ELANE (0.53) LMNAELANEMAPTGAAPKM
Propane SCHEMBL11083413 0.81 KMT2A (0.52) LMNAELANEHSD17B10RAB9AMAPT
SCHEMBL6667339 0.81 LMNA (0.70) LMNAELANEHSD17B10MAPTALDH1A1
Hydroquinone SCHEMBL4313659 0.81 ELANE (0.53) LMNAELANEMAPTGAAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59116662-A None JP disclosed
JP-S59116662-A ELECTROPHOTOGRAPHIC SENSITIVE BODY TOMOEGAWA PAPER CO LTD 1984-07-05 JP disclosed