Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 16/20 | 0.53 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.49 |
| ▸ | CTSD | P07339 | 3/20 | 0.49 |
| ▸ | ECE1 | P42892 | 2/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | BLM | P54132 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11055014 | 0.94 | BACE1 (0.59) | BACE1DPP4DPP8DPP9CTSD | |
| SCHEMBL30591036 | 0.93 | DPP4 (0.52) | BACE1DPP4DPP8DPP9CTSD | |
| SCHEMBL29777801 | 0.91 | DPP4 (0.52) | BACE1DPP4DPP8DPP9CTSD | |
| SCHEMBL30525295 | 0.90 | DPP4 (0.55) | BACE1DPP4DPP8DPP9CTSD | |
| SCHEMBL30011133 | 0.90 | ALOX15 (0.49) | BACE1DPP4DPP8DPP9CTSD | |
| SCHEMBL29725305 | 0.90 | DPP4 (0.49) | BACE1DPP4DPP8DPP9CTSD | |
| SCHEMBL31571448 | 0.89 | BACE1 (0.55) | BACE1DPP4DPP8DPP9CTSD | |
| SCHEMBL30590515 | 0.88 | BACE1 (0.55) | BACE1CTSDECE1 | |
| SCHEMBL11050000 | 0.88 | BACE1 (0.54) | BACE1CTSDECE1 | |
| SCHEMBL31571449 | 0.88 | BACE1 (0.58) | BACE1DPP4DPP8DPP9CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4426324-A | Immunopotentiating peptides | HOFFMANN-LA ROCHE INC. (US) | 1984-01-17 | — | — | US | disclosed |