Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY12 | Q9H244 | 6/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17860588 | 0.88 | ADORA1 (0.40) | P2RY12POLBADORA1 | |
| SCHEMBL4727404 | 0.84 | ADORA1 (0.46) | POLBADORA1 | |
| SCHEMBL4727394 | 0.84 | ADORA1 (0.46) | POLBADORA1 | |
| SCHEMBL18521449 | 0.82 | ADORA1 (0.43) | POLBADORA1 | |
| SCHEMBL17860496 | 0.82 | TYMP (0.42) | P2RY12ADORA1 | |
| SCHEMBL15786368 | 0.81 | P2RY12 (0.42) | P2RY12POLB | |
| SCHEMBL17860563 | 0.80 | TYMP (0.40) | P2RY12POLBADORA1 | |
| SCHEMBL20691331 | 0.80 | P2RY12 (0.38) | P2RY12POLBADORA1 | |
| SCHEMBL11142359 | 0.79 | KDM4E (0.60) | POLB | |
| SCHEMBL24354785 | 0.78 | P2RY12 (0.38) | P2RY12ADORA1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4426517-A | Process for de-cyanoethylating blocked nucleotides | ELI LILLY AND COMPANY (US) | 1984-01-17 | — | — | US | disclosed |
| US-4419509-A | Process for de-cyanoethylating blocked nucleotides | ELI LILLY AND COMPANY (US) | 1983-12-06 | — | — | US | disclosed |
| EP-0075392-A1 | Process for de-cyanoethylating blocked nucleotides | ELI LILLY AND COMPANY (US) | 1983-03-30 | — | — | EP | disclosed |