Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | POLA1 | P09884 | 1/20 | 0.40 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.39 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.39 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9017737 | 0.88 | KDM4E (0.65) | KDM4EPOLA1TAS1R3TAS1R1P2RY1 | |
| SCHEMBL20341100 | 0.82 | KDM4E (0.63) | KDM4EPOLA1TAS1R3TAS1R1P2RY1 | |
| SCHEMBL20341115 | 0.82 | KDM4E (0.56) | KDM4EPOLA1TAS1R3TAS1R1P2RY1 | |
| SCHEMBL12714678 | 0.80 | KDM4E (0.69) | KDM4EPOLA1TAS1R3TAS1R1P2RY1 | |
| SCHEMBL8505718 | 0.79 | KDM4E (0.51) | KDM4EPOLA1TAS1R3TAS1R1P2RY1 | |
| SCHEMBL25504740 | 0.79 | KDM4E (0.66) | KDM4EPOLA1TAS1R3TAS1R1P2RY1 | |
| SCHEMBL11055621 | 0.79 | P2RY12 (0.40) | POLB | |
| SCHEMBL12714686 | 0.79 | KDM4E (0.52) | KDM4ETAS1R3TAS1R1P2RY1POLB | |
| SCHEMBL24209269 | 0.78 | KDM4E (0.53) | KDM4EPOLA1TAS1R3TAS1R1P2RY1 | |
| SCHEMBL23225351 | 0.77 | KDM4E (0.77) | KDM4EPOLA1TAS1R3TAS1R1P2RY1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4419509-A | Process for de-cyanoethylating blocked nucleotides | ELI LILLY AND COMPANY (US) | 1983-12-06 | — | — | US | disclosed |
| EP-0075392-A1 | Process for de-cyanoethylating blocked nucleotides | ELI LILLY AND COMPANY (US) | 1983-03-30 | — | — | EP | disclosed |