Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 4/20 | 0.52 |
| ▸ | CA1 | P00915 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | CA7 | P43166 | 4/20 | 0.52 |
| ▸ | CA9 | Q16790 | 4/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.46 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26126976 | 0.91 | TSHR (0.50) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL11053115 | 0.86 | CA12 (0.57) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL301812 | 0.85 | TSHR (0.55) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL5274828 | 0.85 | TSHR (0.59) | TSHRCA12CA1CA2CA7 | |
| Hydrochloric Acid SCHEMBL28219343 | 0.84 | TSHR (0.53) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL23941176 | 0.82 | TSHR (0.45) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL11274620 | 0.82 | ALDH1A1 (0.53) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL28161602 | 0.82 | TSHR (0.65) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL23941175 | 0.81 | TSHR (0.55) | TSHRCA12CA1CA2CA7 | |
| SCHEMBL6446351 | 0.81 | ALDH1A1 (0.59) | TSHRALDH1A1HSD17B10CYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447595-A | HAZE-FREE PACKAGING MATERIALS | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1984-05-08 | — | — | US | disclosed |
| EP-0102913-A2 | Polyterephthalates having high clarity and process for making same | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1984-03-14 | — | — | EP | disclosed |