Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 7/20 | 0.41 |
| ▸ | TOP2B | Q02880 | 7/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.36 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TUBB | P07437 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10905798 | 0.88 | KDM4E (0.52) | KDM4ESMN1; SMN2CYP1A2LMNATOP2A | |
| SCHEMBL11164745 | 0.81 | KDM4E (0.46) | KDM4ESMN1; SMN2CYP1A2LMNATOP2A | |
| SCHEMBL11051451 | 0.81 | TOP2A (0.41) | KDM4ESMN1; SMN2CYP1A2LMNATOP2A | |
| SCHEMBL10903306 | 0.81 | TOP2A (0.57) | KDM4ETOP2ATOP2BKMT2AALDH1A1 | |
| SCHEMBL10905473 | 0.79 | KDM4E (0.49) | KDM4ESMN1; SMN2CYP1A2LMNATOP2A | |
| SCHEMBL10904846 | 0.79 | KDM4E (0.49) | KDM4ESMN1; SMN2CYP1A2LMNATOP2A | |
| SCHEMBL10905854 | 0.79 | KDM4E (0.49) | KDM4ESMN1; SMN2CYP1A2LMNATOP2A | |
| SCHEMBL11050824 | 0.77 | LMNA (0.48) | KDM4ESMN1; SMN2CYP1A2LMNATOP2A | |
| SCHEMBL11165027 | 0.77 | KDM4E (0.51) | KDM4ESMN1; SMN2CYP1A2LMNATOP2A | |
| SCHEMBL11156854 | 0.77 | LMNA (0.43) | KDM4ESMN1; SMN2CYP1A2LMNATOP2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443447-A | Phenyl-substituted tricyclic antibacterial agents | RIKER LABORATORIES, INC. (US) | 1984-04-17 | — | — | US | disclosed |