SCHEMBL11056024

SCHEMBL11056024

Cc1ccccc1NC(=O)OC1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.55
NPC1 O15118 3/20 0.45
RAB9A P51151 3/20 0.45
P2RX7 Q99572 1/20 0.44
ALDH1A1 P00352 2/20 0.44
HPGD P15428 1/20 0.44
EZH2 Q15910 1/20 0.43
ACHE P22303 5/20 0.43
BCHE P06276 2/20 0.43
CHRM3 P20309 1/20 0.42
TSHR P16473 1/20 0.42
POLB P06746 1/20 0.42
KMT2A Q03164 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29549914 0.83 GAA (0.45) GAANPC1RAB9AALDH1A1POLB
SCHEMBL4449683 0.83 GAA (0.45) GAANPC1RAB9AALDH1A1POLB
SCHEMBL455855 0.82 GAA (0.62) GAANPC1RAB9AALDH1A1EZH2
SCHEMBL2514989 0.81 GAA (0.46) GAANPC1RAB9AALDH1A1POLB
SCHEMBL11125472 0.77 NPC1 (0.61) NPC1RAB9AP2RX7CHRM3TSHR
SCHEMBL11058897 0.76 GAA (0.67) GAAALDH1A1EZH2BCHETSHR
SCHEMBL11057664 0.74 GAA (0.49) GAANPC1RAB9AP2RX7ALDH1A1
SCHEMBL15634694 0.73 GAA (0.58) GAAP2RX7HPGDBCHE
SCHEMBL14409843 0.73 HTT (0.45) GAANPC1RAB9AALDH1A1ACHE
SCHEMBL29793926 0.72 GAA (0.74) GAAALDH1A1EZH2TSHRPOLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4487870-A BLEND OF ETHYLENE-VINYL ACETATE COPOLYMER WITH PHOTOSTABILIZER EXXON RESEARCH & ENGINEERING CO. (US) 1984-12-11 US disclosed
US-4038218-A SPRAY DRYING KAO SOAP CO., LTD. (JA) 1977-07-26 US disclosed