SCHEMBL4449683

SCHEMBL4449683

Cc1ccc(NC(=O)OC2CC(C)(C)NC(C)(C)C2)cc1NC(=O)OC1CC(C)(C)NC(C)(C)C1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.45
ALDH1A1 P00352 3/20 0.44
LMNA P02545 1/20 0.44
MAPK1 P28482 1/20 0.44
HSD17B10 Q99714 1/20 0.43
MEN1 O00255 4/20 0.42
KMT2A Q03164 4/20 0.42
NPC1 O15118 3/20 0.42
RAB9A P51151 3/20 0.42
GLA P06280 1/20 0.41
POLB P06746 1/20 0.40
HTT P42858 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
NLRP3 Q96P20 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
CYP3A4 P08684 2/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
CYP2C19 P33261 1/20 0.37
CYP1A2 P05177 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29549914 1.00 GAA (0.45) GAAALDH1A1LMNAMAPK1HSD17B10
SCHEMBL2514989 0.95 GAA (0.46) GAAALDH1A1LMNAMAPK1HSD17B10
SCHEMBL13227477 0.84 HTT (0.44) GAAALDH1A1LMNAMAPK1MEN1
SCHEMBL11056024 0.83 GAA (0.55) GAAALDH1A1KMT2ANPC1RAB9A
SCHEMBL1841204 0.79 NPC1 (0.64) ALDH1A1LMNAMAPK1MEN1KMT2A
SCHEMBL11057664 0.79 GAA (0.49) GAAALDH1A1MEN1KMT2ANPC1
SCHEMBL11056156 0.79 GAA (0.49) GAAALDH1A1MEN1KMT2ANPC1
SCHEMBL455855 0.79 GAA (0.62) GAAALDH1A1LMNAMAPK1MEN1
SCHEMBL9813714 0.77 HSD17B10 (0.42) ALDH1A1LMNAHSD17B10MEN1KMT2A
SCHEMBL10680690 0.77 HSD17B10 (0.42) ALDH1A1LMNAHSD17B10MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112745497-A Semi-aromatic polyamide resin and preparation method and application thereof 南京开创新材料科技有限公司 2021-05-04 CN claimed
CN-112679728-A Semi-aromatic polyamide resin and preparation method thereof 南京开创新材料科技有限公司 2021-04-20 CN claimed
CN-115028991-A Thermoplastic compositions and articles made therefrom 巴斯夫欧洲公司 2022-09-09 CN disclosed
CN-112708269-B Halogen-free flame-retardant reinforced semi-aromatic polyamide molding composition with specific glass fiber length and molded product 金发科技股份有限公司 2022-07-08 CN disclosed
CN-114672154-A Semi-aromatic polyamide molding composition for LED 金发科技股份有限公司 2022-06-28 CN disclosed
CN-112759923-A Glass fiber reinforced semi-aromatic polyamide molding composition with specific glass fiber length and molded product 金发科技股份有限公司 2021-05-07 CN disclosed
CN-112745497-A Semi-aromatic polyamide resin and preparation method and application thereof 南京开创新材料科技有限公司 2021-05-04 CN disclosed
CN-112708269-A Halogen-free flame-retardant reinforced semi-aromatic polyamide molding composition with specific glass fiber length and molded product 金发科技股份有限公司 2021-04-27 CN disclosed
CN-112679728-A Semi-aromatic polyamide resin and preparation method thereof 南京开创新材料科技有限公司 2021-04-20 CN disclosed
CN-112679948-A Flame-retardant reinforced semi-aromatic polyamide molding composition with specific glass fiber length and molded product 金发科技股份有限公司 2021-04-20 CN disclosed
WO-2020238440-A1 SEMI-AROMATIC POLYAMIDE, METHOD FOR SYNTHESIS THEREOF, AND POLYAMIDE MOLDING COMPOSITION CONSISTING THEREOF 金发科技股份有限公司 2020-12-03 WO disclosed
EP-2868699-A1 RESIN COMPOSITION Teijin Limited (JP) 2015-05-06 EP disclosed
US-20150105521-A1 RESIN COMPOSITION TEIJIN LIMITED (JP) 2015-04-16 US disclosed
US-7550541-B2 Resin composition and molded article, film and fiber each comprising the same TORAY INDUSTRIES, INC. (JP) 2009-06-23 US disclosed
US-20070260019-A1 Resin composition and molded article, film and fiber each comprising the same TORAY INDUSTRIES, INC. (JP) 2007-11-08 US disclosed
US-6977117-B2 Thermoplastic resin integrated structure ASAHI KASEI KABUSHIKI KAISHA (JP) 2005-12-20 US disclosed
US-20010034407-A1 Thermoplastic resin integrated structure ASAHI KASEI KABUSHIKI KAISHA (JP) 2001-10-25 US disclosed
US-6156834-A Polyacetal resin composition ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 2000-12-05 US disclosed
US-6077908-A VINYL POLYMER HAVING A PRIMARY ACID AMIDE GROUP AND AN ACID IMIDE GROUP. EXCELLENT IN HEAT STABILITY IN MOLDING AND WEATHERABILITY AND SUITED FOR USE AS A MOLDING MATERIAL FOR ELECTRIC AND ELECTRONIC PARTS AND AUTOMOTIVE PARTS. ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 2000-06-20 US disclosed