Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.60 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.60 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.51 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.51 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.51 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.51 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11056030 | 1.00 | PLCG1 (0.69) | PLCG1TDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL8954207 | 0.93 | PLCG1 (0.66) | PLCG1TDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL11578082 | 0.93 | PLCG1 (0.66) | PLCG1TDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL11578085 | 0.93 | PLCG1 (0.66) | PLCG1TDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL28528206 | 0.92 | PLCG1 (0.83) | PLCG1TDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL8766584 | 0.92 | PLCG1 (0.83) | PLCG1TDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL8766580 | 0.92 | PLCG1 (0.83) | PLCG1TDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL11577092 | 0.91 | TDP1 (0.64) | PLCG1TDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL11577089 | 0.91 | TDP1 (0.64) | PLCG1TDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL11578880 | 0.90 | PLCG1 (0.59) | PLCG1TDP1L3MBTL1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4440683-A | Cyclization to form cephem ring and azetidinone intermediates therefor | SHIONOGI & CO., LTD. (JP) | 1984-04-03 | — | — | US | disclosed |
| EP-0014567-B1 | PROCESSES FOR PREPARATION OF BETA-LACTAM COMPOUNDS | ELI LILLY AND COMPANY (US) | 1984-01-18 | — | — | EP | disclosed |
| US-4346218-A | DECYCLIZATION OF AN AZETIDINOTHIAZOLINE | SHIONOGI & CO., LTD. (JP) | 1982-08-24 | — | — | US | disclosed |
| US-4332722-A | BICYCLIC AZETIDINOTHIAZOLINES | SHIONOGI & CO., LTD. (JP) | 1982-06-01 | — | — | US | disclosed |
| US-4271305-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1981-06-02 | — | — | US | disclosed |
| US-4226986-A | 7-ACYLAMINO-3-HYDROXY-3-CEPHEM COMPOUND, TRIARYL PHOSPHITE DIHALIDE | ELI LILLY AND COMPANY (US) | 1980-10-07 | — | — | US | disclosed |
| EP-0014567-A1 | Processes for preparation of beta-lactam compounds | ELI LILLY AND COMPANY (US) | 1980-08-20 | — | — | EP | disclosed |
| US-4160085-A | Cyclization to form cephem ring and intermediates therefor | SHIONOGI & CO., LTD. (JP) | 1979-07-03 | — | — | US | disclosed |
| US-4079181-A | INTERMEDIATES FOR 3-HYDROXY-3-CEPHEM COMPOUNDS | SHIONOGI & CO., LTD. (JA) | 1978-03-14 | — | — | US | disclosed |