Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLCG1 | P19174 | 1/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.53 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.53 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.47 |
| ▸ | SLC22A11 | Q9NSA0 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8954207 | 1.00 | PLCG1 (0.66) | PLCG1TDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL11578082 | 1.00 | PLCG1 (0.66) | PLCG1TDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL11056035 | 0.93 | PLCG1 (0.69) | PLCG1TDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL11056030 | 0.93 | PLCG1 (0.69) | PLCG1TDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL9788376 | 0.91 | PLCG1 (0.79) | PLCG1TDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL9788374 | 0.91 | PLCG1 (0.79) | PLCG1TDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL11582598 | 0.91 | PLCG1 (0.79) | PLCG1TDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL11582596 | 0.91 | PLCG1 (0.79) | PLCG1TDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL11094741 | 0.91 | PLCG1 (0.55) | PLCG1TDP1L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL11094744 | 0.91 | PLCG1 (0.55) | PLCG1TDP1L3MBTL1ALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4115643-A | Process for 3-chloro cephalosporins | ELI LILLY AND COMPANY (US) | 1978-09-19 | — | — | US | disclosed |
| US-4048162-A | Process for preparing 3-hydroxy cephalosporins | ELI LILLY AND COMPANY (US) | 1977-09-13 | — | — | US | disclosed |
| US-4008230-A | Process for preparing 3-hydroxy cephalosporins | ELI LILLY AND COMPANY (US) | 1977-02-15 | — | — | US | disclosed |