Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | GLA | P06280 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | TOP2A | P11388 | 2/20 | 0.36 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6245576 | 0.72 | RAB9A (0.51) | NPC1RAB9AALDH1A1MAPTKDM4E | |
| SCHEMBL11054087 | 0.72 | RAB9A (0.51) | NPC1RAB9AALDH1A1MAPTKDM4E | |
| SCHEMBL27492767 | 0.72 | NPC1 (0.47) | NPC1RAB9AALDH1A1MAPTKDM4E | |
| SCHEMBL11058831 | 0.71 | NPC1 (0.50) | NPC1RAB9AALDH1A1MAPTKDM4E | |
| SCHEMBL11057027 | 0.70 | NPC1 (0.49) | NPC1RAB9AALDH1A1MAPTKDM4E | |
| SCHEMBL3234460 | 0.70 | NPC1 (0.41) | NPC1RAB9AALDH1A1MAPTKDM4E | |
| SCHEMBL11054072 | 0.68 | RAB9A (0.47) | NPC1RAB9AALDH1A1MAPTKDM4E | |
| SCHEMBL11695217 | 0.68 | NPC1 (0.46) | NPC1RAB9AALDH1A1MAPTKDM4E | |
| SCHEMBL7648567 | 0.64 | RAB9A (0.86) | NPC1RAB9AALDH1A1MAPTKDM4E | |
| SCHEMBL7277754 | 0.64 | NPC1 (0.58) | NPC1RAB9AALDH1A1MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4474774-A | Acridone substituted phosphorus compounds, compositions containing same and insecticidal method of use | VELSICOL CHEMICAL CORPORATION (US) | 1984-10-02 | — | — | US | disclosed |