Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 1/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 8/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9673557 | 0.81 | AKR1B1 (0.45) | ITGA4 | |
| Alonimid SCHEMBL114140 | 0.74 | CRBN (0.38) | ITGA4CRBNDDB1 | |
| Alonimid SCHEMBL29728701 | 0.74 | CRBN (0.38) | ITGA4CRBNDDB1 | |
| SCHEMBL11057716 | 0.73 | GRIN1 (0.47) | ITGA4 | |
| SCHEMBL5107203 | 0.73 | GSK3B (0.43) | ITGA4 | |
| SCHEMBL11844513 | 0.73 | CRBN (0.40) | ITGA4CRBNDDB1 | |
| SCHEMBL9671705 | 0.69 | AKR1B1 (0.61) | — | |
| SCHEMBL10789485 | 0.69 | KMT2A (0.38) | ITGA4 | |
| SCHEMBL7040158 | 0.68 | KDM1A (0.46) | — | |
| SCHEMBL28498656 | 0.68 | GRIN1 (0.45) | ITGA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4486592-A | ANTIARRHYTHMIA AGENTS | ELI LILLY AND COMPANY (US) | 1984-12-04 | — | — | US | disclosed |