Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.77 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9795430 | 0.96 | TSHR (0.71) | TSHRLMNACYP2C9CA1CA2 | |
| SCHEMBL3089224 | 0.96 | — | — | |
| SCHEMBL1852318 | 0.96 | — | — | |
| SCHEMBL3089221 | 0.96 | — | — | |
| SCHEMBL13889158 | 0.96 | — | — | |
| Cyclohexanol SCHEMBL29093120 | 0.93 | TSHR (0.67) | TSHRLMNACYP2C9CA1CA2 | |
| SCHEMBL13888941 | 0.92 | TSHR (0.64) | TSHRLMNACYP2C9CA1CA2 | |
| SCHEMBL13889159 | 0.92 | TSHR (0.64) | TSHRLMNACYP2C9CA1CA2 | |
| SCHEMBL10795387 | 0.92 | TSHR (0.64) | TSHRLMNACYP2C9CA1CA2 | |
| SCHEMBL2154470 | 0.92 | TSHR (0.64) | TSHRLMNACYP2C9CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4433134-A | POLYOXYALKYLENEPOLYOL | PHILLIPS PETROLEUM COMPANY (US) | 1984-02-21 | — | — | US | disclosed |
| EP-0056066-A1 | Process for the preparation of a polythiol polymer, sealant composition and sealant | PHILLIPS PETROLEUM COMPANY (US) | 1982-07-21 | — | — | EP | disclosed |
| US-4307225-A | STORAGE STABLE | PHILLIPS PETROLEUM COMPANY (US) | 1981-12-22 | — | — | US | disclosed |
| US-4267307-A | NONTACKY SURFACES BY CURING A POLYOXYALKYLENE GLYCOL WITH END GROUPS CONTAINING PRIMARY HYDROXYL GROUPS MODIFIED BY A MERCAPTO ACID OR ESTER | PHILLIPS PETROLEUM COMPANY (US) | 1981-05-12 | — | — | US | disclosed |
| US-4232167-A | Preparation of alkyl mercaptocarboxylate/dialkyl thiodicarboxylate mixture using sulfur and/or water cocatalyst | PHILLIPS PETROLEUM COMPANY (US) | 1980-11-04 | — | — | US | disclosed |
| US-4224436-A | MERCAPTAN-TERMINATED POLYETHER; THERMAL STABILITY | PHILLIPS PETROLEUM COMPANY (US) | 1980-09-23 | — | — | US | disclosed |
| US-4113707-A | Poly(oxyalkylene)-polyester-poly(sulfide)-polythiol prepared by ester interchange | PHILLIPS PETROLEUM COMPANY (US) | 1978-09-12 | — | — | US | disclosed |