Propionaldehyde

Propionaldehyde

SCHEMBL11056597

CCC=O.Cc1cccc(C=O)c1

nearest known ligand 0.53

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.53
MAOB P27338 3/20 0.53
TP53 P04637 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
NPC1 O15118 1/20 0.48
CASP3 P42574 1/20 0.48
SENP8 Q96LD8 1/20 0.48
SENP7 Q9BQF6 1/20 0.48
SENP6 Q9GZR1 1/20 0.48
ALDH1A1 P00352 2/20 0.45
FBP1 P09467 1/20 0.44
ACHE P22303 1/20 0.42
PTGS1 P23219 2/20 0.42
PTGS2 P35354 2/20 0.42
ALOX5 P09917 1/20 0.42
CYP2A6 P11509 2/20 0.41
UNG P13051 1/20 0.41
RELA Q04206 1/20 0.41
LMNA P02545 1/20 0.40
HTT P42858 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29456572 0.89
SCHEMBL7227961 0.89 TP53 (0.60) MAOAMAOBTP53TDP1NPC1
SCHEMBL65797 0.89
Hydrochloric Acid SCHEMBL22772087 0.87 TP53 (0.58) MAOAMAOBTP53TDP1NPC1
Water SCHEMBL27363683 0.87 TP53 (0.58) MAOAMAOBTP53TDP1NPC1
M-Xylene SCHEMBL28139324 0.85 ACHE (0.60) MAOAMAOBTP53TDP1NPC1
Formic Acid SCHEMBL26965059 0.83 TP53 (0.54) MAOAMAOBTP53TDP1NPC1
SCHEMBL1611151 0.83 TP53 (0.58) MAOAMAOBTP53TDP1NPC1
SCHEMBL6480084 0.82 TP53 (0.52) MAOAMAOBTP53TDP1NPC1
SCHEMBL6057077 0.82 CYP2A6 (0.67) MAOAMAOBTP53TDP1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4430252-A ALDEHYDE, KETONE OR ETHER SOLVENT; METAL HYDROCARBOXIDES; PHOSPHORUS-OXYGEN COMPOUND EXXON RESEARCH & ENGINEERING CO. (US) 1984-02-07 US disclosed