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Sugi Predict / Compounds / SCHEMBL11057211

SCHEMBL11057211

SCHEMBL11057211

Cc1c(CO/N=C(/c2ccc(C(F)(F)F)cc2)C2CC2)cccc1-c1ccccc1

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ CD274 Q9NZQ7 15/20 0.40
▸ PDCD1 Q15116 1/20 0.40
▸ PPARG P37231 1/20 0.40
▸ PPARD Q03181 1/20 0.40
▸ PPARA Q07869 1/20 0.40
▸ MEN1 O00255 1/20 0.39
▸ KMT2A Q03164 1/20 0.39
▸ L3MBTL1 Q9Y468 1/20 0.39
▸ EPHX1 P07099 1/20 0.37
▸ TACR1 P25103 1/20 0.36
▸ PTGDR2 Q9Y5Y4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11057216 1.00 CD274 (0.40) CD274PDCD1PPARGPPARDPPARA
SCHEMBL11057836 0.91 CD274 (0.41) CD274PDCD1MEN1KMT2AL3MBTL1
SCHEMBL11057841 0.91 CD274 (0.41) CD274PDCD1MEN1KMT2AL3MBTL1
SCHEMBL11056212 0.89 CD274 (0.48) CD274PDCD1MEN1KMT2AL3MBTL1
SCHEMBL11056231 0.89 CD274 (0.48) CD274PDCD1MEN1KMT2AL3MBTL1
SCHEMBL11057242 0.89 CD274 (0.43) CD274PDCD1MEN1KMT2AL3MBTL1
SCHEMBL11057238 0.89 CD274 (0.43) CD274PDCD1MEN1KMT2AL3MBTL1
SCHEMBL11060036 0.88 CD274 (0.45) CD274PDCD1MEN1KMT2AL3MBTL1
SCHEMBL11060029 0.88 CD274 (0.45) CD274PDCD1MEN1KMT2AL3MBTL1
SCHEMBL11048723 0.86 CD274 (0.43) CD274PDCD1MEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4434182-A Insecticidal substituted-biphenylmethyl oxime ethers FMC CORPORATION (US) 1984-02-28 — — US disclosed