SCHEMBL11060029

SCHEMBL11060029

Cc1c(CO/N=C(/c2ccc(OC(F)(F)F)cc2)C2CC2)cccc1-c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
CD274 Q9NZQ7 14/20 0.45
PDCD1 Q15116 3/20 0.45
HCRTR1 O43613 2/20 0.39
HCRTR2 O43614 2/20 0.39
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
FFAR1 O14842 1/20 0.38
FFAR4 Q5NUL3 1/20 0.38
CCR5 P51681 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11060036 1.00 CD274 (0.45) CD274PDCD1HCRTR1HCRTR2MEN1
SCHEMBL11057211 0.88 CD274 (0.40) CD274PDCD1MEN1KMT2AL3MBTL1
SCHEMBL11057216 0.88 CD274 (0.40) CD274PDCD1MEN1KMT2AL3MBTL1
SCHEMBL11056212 0.88 CD274 (0.48) CD274PDCD1MEN1KMT2AL3MBTL1
SCHEMBL11056231 0.88 CD274 (0.48) CD274PDCD1MEN1KMT2AL3MBTL1
SCHEMBL11057242 0.87 CD274 (0.43) CD274PDCD1MEN1KMT2AL3MBTL1
SCHEMBL11057238 0.87 CD274 (0.43) CD274PDCD1MEN1KMT2AL3MBTL1
SCHEMBL11048772 0.86 CD274 (0.39) CD274PDCD1MEN1KMT2AL3MBTL1
SCHEMBL11048770 0.86 CD274 (0.39) CD274PDCD1MEN1KMT2AL3MBTL1
SCHEMBL11057806 0.86 CD274 (0.43) CD274PDCD1MEN1KMT2AL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4434182-A Insecticidal substituted-biphenylmethyl oxime ethers FMC CORPORATION (US) 1984-02-28 US disclosed