Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | NAAA | Q02083 | 2/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9155398 | 1.00 | NPC1 (0.47) | NPC1RAB9ASMN1; SMN2LTA4HLMNA | |
| SCHEMBL10761888 | 0.98 | LTA4H (0.47) | NPC1RAB9ASMN1; SMN2LTA4HLMNA | |
| SCHEMBL10717745 | 0.92 | LTA4H (0.47) | NPC1RAB9ASMN1; SMN2LTA4HLMNA | |
| SCHEMBL29048524 | 0.92 | NPC1 (0.42) | NPC1RAB9ASMN1; SMN2LTA4HLMNA | |
| SCHEMBL15384168 | 0.91 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2LTA4HLMNA | |
| SCHEMBL4384773 | 0.86 | HTT (0.44) | SMN1; SMN2LMNAHTR2ATSHRKCNH2 | |
| SCHEMBL2502300 | 0.85 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2LTA4HLMNA | |
| SCHEMBL2502304 | 0.85 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2LTA4HLMNA | |
| SCHEMBL28676094 | 0.85 | KCNH2 (0.55) | NPC1RAB9ASMN1; SMN2LMNAHTR2A | |
| SCHEMBL27951679 | 0.85 | KCNH2 (0.55) | NPC1RAB9ASMN1; SMN2LMNAHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460445-A | PROPYLENE POLYMERS | MILLIKEN RESEARCH CORPORATION (US) | 1984-07-17 | — | — | US | claimed |
| US-4460445-A | PROPYLENE POLYMERS | MILLIKEN RESEARCH CORPORATION (US) | 1984-07-17 | — | — | US | disclosed |