SCHEMBL11057739

SCHEMBL11057739

C#CCC(C)(CCCCCC)O[Si](C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.30
HTT P42858 3/20 0.30
LMNA P02545 2/20 0.30
RAB9A P51151 2/20 0.30
MEN1 O00255 1/20 0.30
GAA P10253 1/20 0.30
MAPT P10636 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10717358 0.93
SCHEMBL8104791 0.93
SCHEMBL11252226 0.81
SCHEMBL8196713 0.77
SCHEMBL10747266 0.76
SCHEMBL11339828 0.75
SCHEMBL9156765 0.73 GGPS1 (0.31)
SCHEMBL10615507 0.72
SCHEMBL11337219 0.72
SCHEMBL14298962 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4477388-A CHEMICAL INTERMEDIATES FOR PROSTAGLANDINS AMERICAN CYANAMID COMPANY (US) 1984-10-16 US disclosed