⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10717358 | 1.00 | — | — | |
| SCHEMBL11057739 | 0.93 | SMN1; SMN2 (0.30) | — | |
| SCHEMBL8196713 | 0.84 | — | — | |
| SCHEMBL11252226 | 0.84 | — | — | |
| SCHEMBL10747266 | 0.78 | — | — | |
| SCHEMBL11339828 | 0.78 | — | — | |
| SCHEMBL10915058 | 0.76 | — | — | |
| SCHEMBL11337219 | 0.75 | — | — | |
| SCHEMBL10615507 | 0.75 | — | — | |
| SCHEMBL11587402 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 38 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0643063-B1 | Process for preparing a higher cuprate complex | SEARLE & CO (US) | 2000-01-26 | — | — | EP | disclosed |
| US-6013823-A | AS CHEMICAL INTERMEDIATES; UTROTONIC AGENTS, BRONCHODIALATORS | NEW PHARMA INTERNATIONAL CORP. (UY) | 2000-01-11 | — | — | US | disclosed |
| US-5817694-A | OXYTOCICS | NEW PHARMA INTERNATIONAL CORP. (UY) | 1998-10-06 | — | — | US | disclosed |
| EP-0574185-B1 | PGE1 analogs | NEWPHARMA INTERNATIONAL CORP (UY) | 1997-09-03 | — | — | EP | disclosed |
| US-5449673-A | Analgesics | G. D. SEARLE & CO. (US) | 1995-09-12 | — | — | US | disclosed |
| EP-0452843-B1 | Process for preparing prostaglandin analogs using organozirconium compounds | SEARLE & CO (US) | 1995-06-14 | — | — | EP | disclosed |
| EP-0643063-A2 | Process for preparing a higher cuprate complex | G.D. Searle & Co. (US) | 1995-03-15 | — | — | EP | disclosed |
| EP-0574185-A2 | PGE1 analogs | NEWPHARMA INTERNATIONAL CORPORATION (UY) | 1993-12-15 | — | — | EP | disclosed |
| US-5252763-A | Higher order cuprate complexes from alkyne, zirconocene chloride hydride, alkyllithium and cuprous cyanide | G. D. SEARLE & CO. (US) | 1993-10-12 | — | — | US | disclosed |
| WO-1993007132-A1 | 10-ACYL-DIBENZ(B,F)(1,4)-OXAZEPINES AND THEIR THIAZEPINES AND DIAZEPINES ANALOGUES USEFUL AS PROSTAGLANDIN ANTAGONISTS | G.D. SEARLE & CO. (US) | 1993-04-15 | — | — | WO | disclosed |
| US-4179451-A | HYPOTENSIVE, ANTIULCER, BRONCHODILATOR, ANTICONVULSANTS OR ANTIMICROBIAL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1979-12-18 | — | — | US | disclosed |
| US-4172839-A | PROSTAGLANDINS | AMERICAN CYANAMID COMPANY (US) | 1979-10-30 | — | — | US | disclosed |
| US-4170597-A | 1-Hydroxymethyl-1-oxo-prostane derivatives of the E2 series | AMERICAN CYANAMID COMPANY (US) | 1979-10-09 | — | — | US | disclosed |
| US-4165331-A | PROSTAGLANDINS/AND DERIVATIVES | AMERICAN CYANAMID COMPANY (US) | 1979-08-21 | — | — | US | disclosed |
| EP-0002590-A1 | Novel prostaglandin compounds, processes for the preparation thereof and pharmaceutical compositions containing them | AMERICAN CYANAMID COMPANY (US) | 1979-06-27 | — | — | EP | disclosed |
| US-4154959-A | 11-(2-Hydroxyethylthio)prostenoic acid E series derivatives | AMERICAN CYANAMID COMPANY (US) | 1979-05-15 | — | — | US | disclosed |
| US-4154954-A | BRONCHODILATOR AGENTS; ANTIINFLAMMATORY AGENTS | AMERICAN CYANAMID COMPANY (US) | 1979-05-15 | — | — | US | disclosed |
| US-4107441-A | HYPOTENSIVE, ANTIULCER, BRONCHODILATORS, ANTIMICROBIAL, ANTICONVULSANTS | AMERICAN CYANAMID COMPANY (US) | 1978-08-15 | — | — | US | disclosed |
| US-4087447-A | Anti-secretory prostaglandins intermediates | G. D. SEARLE & CO. (US) | 1978-05-02 | — | — | US | disclosed |
| US-4085272-A | BRONCHODILATORS, INFLAMMATORY MEDEATOR RELEASE INHIBITORS | AMERICAN CYANAMID COMPANY (US) | 1978-04-18 | — | — | US | disclosed |