Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALPI | P09923 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813246 | 0.84 | KIF11 (0.61) | KIF11PKMCYP1A2CYP2D6SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL9813243 | 0.83 | KIF11 (0.59) | KIF11PKMCYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL11194800 | 0.80 | KIF11 (0.64) | KIF11PKMCYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL11194798 | 0.80 | KIF11 (0.64) | KIF11PKMCYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL11077265 | 0.80 | KIF11 (0.60) | KIF11PKMCYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL9717076 | 0.79 | KIF11 (0.58) | KIF11PKMCYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL27591055 | 0.79 | KIF11 (0.58) | KIF11PKMCYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL27591052 | 0.79 | KIF11 (0.58) | KIF11PKMCYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL27546317 | 0.79 | KIF11 (0.58) | KIF11PKMCYP1A2CYP2D6SMN1; SMN2 | |
| SCHEMBL11512005 | 0.78 | ALPI (0.58) | KIF11PKMCRHBPCRHR2ALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4467101-A | CEPHALOSPORIN PRECURSORS | CIBA-GEIGY CORPORATION (US) | 1984-08-21 | — | — | US | disclosed |
| US-4374134-A | Cephalosporin compounds with terminal aminocarboxylic acid groupings and anti-bacterial use thereof | CIBA-GEIGY CORPORATION (US) | 1983-02-15 | — | — | US | disclosed |