Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GMNN | O75496 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | BHMT | Q93088 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL851975 | 0.75 | CYP2D6 (0.50) | CYP2D6HIF1APOLBMAPTGMNN | |
| SCHEMBL27845735 | 0.73 | CYP2D6 (0.48) | CYP2D6HIF1APOLBMAPTGMNN | |
| SCHEMBL2034998 | 0.73 | CYP2D6 (1.00) | CYP2D6HIF1APOLBMAPTGMNN | |
| SCHEMBL144220 | 0.73 | — | — | |
| SCHEMBL11055862 | 0.72 | ALDH1A1 (0.48) | CYP2D6HIF1AMAPTHSD17B10CYP2C19 | |
| SCHEMBL11052979 | 0.72 | HSD17B10 (0.50) | CYP2D6HIF1APOLBMAPTGMNN | |
| Ammonia Solution, Strong SCHEMBL28227410 | 0.70 | CYP2D6 (0.92) | CYP2D6HIF1APOLBMAPTGMNN | |
| SCHEMBL623697 | 0.69 | — | — | |
| SCHEMBL1324929 | 0.67 | CYP2D6 (0.73) | CYP2D6HIF1APOLBMAPTGMNN | |
| Ethylene SCHEMBL28577554 | 0.67 | CYP2D6 (0.86) | CYP2D6HIF1APOLBMAPTGMNN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4434161-A | ANTICHOLESTEROL | SANDOZ, INC. (US) | 1984-02-28 | — | — | US | disclosed |