Known targets — ChEMBL curated mechanism
ACHECHKACHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGHRH2OPRM1
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL401731 | 0.95 | ALDH1A1 (0.36) | ALDH1A1 | |
| SCHEMBL27443379 | 0.92 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL27489614 | 0.92 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL27464350 | 0.92 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL27995143 | 0.92 | ALDH1A1 (0.35) | ALDH1A1 | |
| SCHEMBL1999637 | 0.86 | — | — | |
| SCHEMBL1999636 | 0.86 | — | — | |
| SCHEMBL10700670 | 0.86 | — | — | |
| SCHEMBL11865018 | 0.85 | ALDH1A1 (0.31) | ALDH1A1 | |
| Carbon Monoxide SCHEMBL3890490 | 0.85 | ALDH1A1 (0.36) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4485256-A | FOR PREPARATION OF ADIPIC ACID | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-11-27 | — | — | US | disclosed |