SCHEMBL11059338

SCHEMBL11059338

O=[PH](OC1=CCCCC1)OC1=CCCCC1

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
GSTP1 P09211 1/20 0.30
TYMP P19971 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4163645 0.93 ALDH1A1 (0.31) HDAC4HDAC2HDAC8HDAC6
SCHEMBL28980042 0.83 HDAC4 (0.34) HDAC4HDAC2HDAC8HDAC6
SCHEMBL4163648 0.76
SCHEMBL1134992 0.75 KDM1A (0.36) HDAC4HDAC2HDAC8HDAC6
SCHEMBL10876862 0.72 KDM1A (0.34) HDAC4HDAC2HDAC8HDAC6
SCHEMBL8414433 0.72 KDM1A (0.34) HDAC4HDAC2HDAC8HDAC6
SCHEMBL10876868 0.72 KDM1A (0.34) HDAC4HDAC2HDAC8HDAC6
SCHEMBL10876875 0.72 KDM1A (0.34) HDAC4HDAC2HDAC8HDAC6
SCHEMBL28422594 0.70 KDM1A (0.33) HDAC4HDAC2HDAC8HDAC6
SCHEMBL11783718 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115724887-A Process for the synthesis of chiral alpha-phosphorus compounds 武汉大学 2023-03-03 CN disclosed
US-4446061-A FIREPROOFING, SMOKELESS, PHOSPHITE/PHOSPHONATE MONSANTO COMPANY (US) 1984-05-01 US disclosed
US-4313761-A FIREPROOFING AND SMOKE SUPPRESSANTS MONSANTO COMPANY (US) 1982-02-02 US disclosed
US-4260542-A FLAME RETARDANTS, SMOKE SUPPRESSANTS MONSANTO COMPANY (US) 1981-04-07 US disclosed
US-4206133-A FLAME RETARDANTS AND SMOKE SUPPRESSANTS MONSANTO COMPANY (US) 1980-06-03 US disclosed
US-4133823-A FIREPROOFING, SMOKELESS MONSANTO COMPANY (US) 1979-01-09 US disclosed