Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.41 |
| ▸ | DRD1 | P21728 | 2/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | DRD3 | P35462 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29167883 | 0.86 | SLC6A3 (0.44) | SLC6A3CHRM2ADRA2ACHRM1DRD1 | |
| SCHEMBL16334384 | 0.75 | NPC1 (0.42) | SLC6A3SLC6A2ALDH1A1SLC6A4MAPK1 | |
| SCHEMBL10029719 | 0.74 | PTGER4 (0.41) | SLC6A3CHRM2ADRA2ACHRM1DRD1 | |
| SCHEMBL13686149 | 0.74 | SLC6A3 (0.46) | SLC6A3CHRM2ADRA2ACHRM1DRD1 | |
| SCHEMBL17447727 | 0.73 | IDO1 (0.47) | SLC6A3CHRM2ADRA2ACHRM1DRD1 | |
| SCHEMBL4049568 | 0.72 | MEN1 (0.33) | SLC6A3ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL11930056 | 0.72 | SLC6A3 (0.44) | SLC6A3CHRM2ADRA2ACHRM1DRD1 | |
| SCHEMBL10136515 | 0.72 | SLC6A3 (0.44) | SLC6A3CHRM2ADRA2ACHRM1DRD1 | |
| SCHEMBL19169500 | 0.71 | SLC6A3 (0.37) | SLC6A3CHRM2ADRA2ACHRM1DRD1 | |
| SCHEMBL11719808 | 0.71 | SLC6A3 (0.46) | SLC6A3CYP2D6MEN1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447605-A | Di(tri-lower alkylstannyl)pyrimidine derivative and a process for producing the same | RIKAGAKU KENKYUSHO (JP) | 1984-05-08 | — | — | US | disclosed |
| US-4324895-A | REACTION BETWEEN BIS(TRI-LOWER ALKYLSTANNYL)-5-HALOGENOURACIL AND 2-SUBSTITUTED TETRAHYDROFURAN | RIKAGAKU KENKYUSHO (JP) | 1982-04-13 | — | — | US | disclosed |