Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20357958 | 0.84 | TDP1 (0.42) | MAPTTSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL4095052 | 0.84 | MAPT (0.49) | MAPTTSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL5953091 | 0.81 | TSHR (0.49) | MAPTTSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL2467874 | 0.81 | MAPT (0.49) | MAPTTSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL19511923 | 0.81 | MAPT (0.62) | MAPTTSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL3243151 | 0.79 | MAPT (0.60) | MAPTTSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL6296310 | 0.77 | MAPT (0.40) | MAPTTSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL10937606 | 0.77 | PDK1 (0.50) | MAPTTSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL9378154 | 0.77 | MAPT (0.58) | MAPTTSHRCYP1A2CYP2C9CYP2C19 | |
| SCHEMBL596168 | 0.76 | MAPT (0.62) | MAPTTSHRCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4470826-A | HAIR DYES, NITRO DYES, DIRECT DYES | L'OREAL (FR) | 1984-09-11 | — | — | US | disclosed |