Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28757029 | 0.84 | GAA (0.40) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL8759600 | 0.81 | GAA (0.38) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL8159636 | 0.81 | GAA (0.38) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL8760131 | 0.77 | MGAM (0.34) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL10456362 | 0.77 | MGAM (0.34) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL10456327 | 0.77 | MGAM (0.34) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL9796959 | 0.76 | GAA (0.36) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL9796952 | 0.76 | GAA (0.36) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL11401898 | 0.76 | MGAM (0.33) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL10835384 | 0.76 | MGAM (0.33) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4468521-A | Method of producing gamma-halogeno-delta unsaturated carboxylic acid esters | KURARAY CO., LTD. (JP) | 1984-08-28 | — | — | US | disclosed |
| US-4454343-A | Intermediates in a process for preparing dihalovinylcyclopropanecarboxylates | FMC CORPORATION (US) | 1984-06-12 | — | — | US | disclosed |