Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10456327 | 0.94 | MGAM (0.34) | MGAMGAASIMGAM2HSD11B1 | |
| SCHEMBL10457808 | 0.93 | KDM4E (0.32) | MGAMGAASIMGAM2HSD11B1 | |
| SCHEMBL10457689 | 0.91 | MGAM (0.32) | MGAMGAASIMGAM2HSD11B1 | |
| SCHEMBL11401898 | 0.89 | MGAM (0.33) | MGAMGAASIMGAM2HSD11B1 | |
| SCHEMBL10835148 | 0.88 | HSD11B1 (0.31) | MGAMGAASIMGAM2HSD11B1 | |
| SCHEMBL10456362 | 0.88 | MGAM (0.34) | MGAMGAASIMGAM2HSD11B1 | |
| SCHEMBL11394873 | 0.85 | NAAA (0.36) | ALDH1A1L3MBTL1 | |
| SCHEMBL8159636 | 0.85 | GAA (0.38) | MGAMGAASIMGAM2HSD11B1 | |
| SCHEMBL8759600 | 0.85 | GAA (0.38) | MGAMGAASIMGAM2HSD11B1 | |
| SCHEMBL8760006 | 0.84 | TSHR (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4378316-A | INTERMEDIATES FOR CYCLOPROPANE-CARBOXYLIC ESTERS; INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1983-03-29 | — | — | US | claimed |
| WO-2021144812-A1 | PROCESS FOR PREPARATION OF CYCLOPROPANE CARBOXYLIC ACIDS AND INTERMEDIATES THEREOF | SRF LIMITED (IN) | 2021-07-22 | — | — | WO | disclosed |
| EP-0566643-B1 | PROCESS FOR PREPARING HALOGENATED COMPOUNDS | ZENECA LTD (GB) | 1997-05-28 | — | — | EP | disclosed |
| US-5258547-A | Process for preparing halogenated compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-11-02 | — | — | US | disclosed |
| EP-0566643-A1 | PROCESS FOR PREPARING HALOGENATED COMPOUNDS. | ICI PLC (GB) | 1993-10-27 | — | — | EP | disclosed |
| WO-1992012115-A1 | PROCESS FOR PREPARING HALOGENATED COMPOUNDS | ZENECA LIMITED (GB) | 1992-07-23 | — | — | WO | disclosed |
| WO-1992012125-A1 | PREPARATION OF SULPHONYL HALIDES | ZENECA LIMITED (GB) | 1992-07-23 | — | — | WO | disclosed |
| US-4970330-A | INSECTICIDES, PESTICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-11-13 | — | — | US | disclosed |
| EP-0069761-B1 | (+)-4-SUBSTITUTED-2-INDANOLS AND INSECTICIDAL ESTER DERIVATIVES | FMC Corporation (US) | 1985-08-14 | — | — | EP | disclosed |
| US-4442296-A | LARVICIDES | FMC CORPORATION (US) | 1984-04-10 | — | — | US | disclosed |
| US-4330675-A | INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1982-05-18 | — | — | US | disclosed |
| EP-0051355-A1 | An improved process for the preparation of certain cyclopropane pyrethroid intermediates having a high cis-content | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-05-12 | — | — | EP | disclosed |
| US-4263319-A | CYCLOPROPYL ESTERS | FMC CORPORATION (US) | 1981-04-21 | — | — | US | disclosed |
| US-4258202-A | INSECTICIDES OF THE PYRETHROID TYPE | MONTEDISON S.P.A. (IT) | 1981-03-24 | — | — | US | disclosed |
| US-4252820-A | Arthropodicidal 2,2-dimethyl-3-(2-perfluoroalkyl-2-perhaloalkyl-vinyl)-cyclopropanecarboxylic acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1981-02-24 | — | — | US | disclosed |
| US-4243677-A | APHIDICIDES; PHOTOSTABILITY | FMC CORPORATION (US) | 1981-01-06 | — | — | US | disclosed |
| US-4238505-A | HIGH TOXICITY | FMC CORPORATION (US) | 1980-12-09 | — | — | US | disclosed |
| US-4235927-A | Insecticidal benzylfurylmethyl perhaloalkylvinylcyclopropanecarboxylates | FMC CORPORATION (US) | 1980-11-25 | — | — | US | disclosed |
| US-4183948-A | INSECTICIDE SYNERGIST | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1980-01-15 | — | — | US | disclosed |
| EP-0003336-A2 | Insecticidal perhaloalkylvinylcyclopropanecarboxylates | FMC Corporation (US) | 1979-08-08 | — | — | EP | disclosed |