Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.60 |
| ▸ | RAB9A | P51151 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.60 |
| ▸ | POLB | P06746 | 3/20 | 0.60 |
| ▸ | PLG | P00747 | 3/20 | 0.60 |
| ▸ | KLK1 | P06870 | 2/20 | 0.60 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.60 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.57 |
| ▸ | PLAU | P00749 | 2/20 | 0.56 |
| ▸ | F2 | P00734 | 1/20 | 0.56 |
| ▸ | F10 | P00742 | 1/20 | 0.56 |
| ▸ | PLAT | P00750 | 1/20 | 0.56 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29403111 | 0.89 | NPC1 (0.73) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL2743095 | 0.89 | NPC1 (0.73) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL30637146 | 0.89 | NPC1 (0.73) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL11063219 | 0.85 | MEN1 (0.65) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL5426499 | 0.82 | KMT2A (0.84) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL13380512 | 0.81 | KMT2A (0.73) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL30897005 | 0.81 | KMT2A (0.73) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL9403388 | 0.80 | PLG (0.56) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL11058408 | 0.79 | NPC1 (0.67) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL330715 | 0.78 | TMPRSS4 (0.65) | NPC1RAB9AMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4451398-A | Dyes containing imidazolymethylene groups | BASF AKTIENGESELLSCHAFT (DE) | 1984-05-29 | — | — | US | disclosed |
| US-4143034-A | LIGHTFAST | STERLING DRUG INC. (US) | 1979-03-06 | — | — | US | disclosed |