SCHEMBL5426499

SCHEMBL5426499

O=C(Nc1ccc(NC(=O)c2cc3ccccc3cc2O)cc1)c1cc2ccccc2cc1O

nearest known ligand 0.84

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.84
MEN1 O00255 8/20 0.84
RAB9A P51151 7/20 0.84
NPC1 O15118 6/20 0.84
POLB P06746 4/20 0.84
CASP3 P42574 1/20 0.79
SENP7 Q9BQF6 1/20 0.79
SENP6 Q9GZR1 1/20 0.79
PLG P00747 3/20 0.77
KLK1 P06870 2/20 0.77
KLK6 Q92876 2/20 0.77
MAPT P10636 3/20 0.73
MAPK1 P28482 1/20 0.73
APOBEC3A P31941 1/20 0.73
APOBEC3G Q9HC16 1/20 0.73
PLAU P00749 2/20 0.71
F2 P00734 1/20 0.71
F10 P00742 1/20 0.71
PLAT P00750 1/20 0.71
MITF O75030 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15478030 0.95 KMT2A (0.77) KMT2AMEN1RAB9ANPC1POLB
SCHEMBL57970 0.95 MEN1 (0.77) KMT2AMEN1RAB9ANPC1POLB
SCHEMBL30084384 0.95 MEN1 (0.77) KMT2AMEN1RAB9ANPC1POLB
SCHEMBL29890853 0.95 MEN1 (0.77) KMT2AMEN1RAB9ANPC1POLB
SCHEMBL10865627 0.92 NPC1 (0.73) KMT2AMEN1RAB9ANPC1POLB
SCHEMBL13380502 0.92 KMT2A (0.73) KMT2AMEN1RAB9ANPC1POLB
SCHEMBL2743095 0.92 NPC1 (0.73) KMT2AMEN1RAB9ANPC1POLB
SCHEMBL10340544 0.92 KMT2A (0.77) KMT2AMEN1RAB9ANPC1POLB
SCHEMBL10597427 0.92 KMT2A (0.73) KMT2AMEN1RAB9ANPC1POLB
SCHEMBL2743097 0.92 KMT2A (1.00) KMT2AMEN1RAB9ANPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7309389-B2 Preparation of azo colorants in microreactors and their use in electrophotographic toners and developers, powder coatings, ink jet inks and electronic medias CLARIANT FINANCE (BVI) LIMITED (VG) 2007-12-18 US disclosed
US-20070213516-A1 Process For Producing High-Purity Azo Dyes HOELLEIN VOLKER 2007-09-13 US disclosed
US-7135266-B2 Preparation of azo colorants in microreactors and their use in electrophotographic toners and developers, powder coatings, ink jet inks and electronic medias CLARIANT FINANCE (BVI) LIMITED (VG) 2006-11-14 US disclosed
US-20060228640-A1 Preparation of azo colorants in microreactors and their use in electrophotographic toners and developers, powder coatings, ink jet inks and electronic medias CLARIANT FINANCE (BVI) LIMITED 2006-10-12 US disclosed
US-20060042117-A1 Method and device for carrying out chemical and physical methods CLARIANT PRODUKTE (DEUTSCHLAND) GMBH (DE) 2006-03-02 US disclosed
US-20040131507-A1 Adjustment of concentration of reactants; rotating electrodes transverse to fluid flow; process control SAITMACHER KLAUS (DE) 2004-07-08 US disclosed
US-20030083410-A1 Preparation of azo colorants in microreactors and their use in electrophotographic toners and developers, powder coatings, ink jet inks and electronic medias CLARIANT FINANCE ( BVI) LIMITED 2003-05-01 US disclosed
US-6548647-B2 Spraying coupling components in solution or suspension to collide in reactor chamber, then pressurizing to remove; useful for offset printing inks CLARIANT GMBH (DE) 2003-04-15 US disclosed
US-6469147-B2 DIAZOTIZATION CLARIANT FINANCE (BVI) LIMITED (VG) 2002-10-22 US disclosed
US-20010029294-A1 Preparation of azo colorants in microreactors CLARIANT INTERNATIONAL LTD. 2001-10-11 US disclosed
US-4206144-A N,N-Dialkyl-N-aminoalkyl-N-(amino or nitro)phenylalkyl- and N-methyl-N-[3-(amino or nitro)phenoxy-2-hydroxy-1-propyl]-N,N-bis(3-aminopropyl)quaternary ammonium salts STERLING DRUG INC. (US) 1980-06-03 US disclosed
US-4146558-A Azo dyestuff intermediate nitro- or aminobenzenes ring-substituted by a quaternized amine alkyl or amino-alkoxy group STERLING DRUG INC. (US) 1979-03-27 US disclosed
US-4103092-A Water-soluble quaternary ammonium non-heterocyclic azo dyestuffs STERLING DRUG INC. (US) 1978-07-25 US disclosed
US-4065500-A Water-soluble quaternary ammonium azo dyestuffs STERLING DRUG INC. (US) 1977-12-27 US disclosed
US-3996282-A Water-soluble quaternary ammonium dyestuffs STERLING DRUG INC. (US) 1976-12-07 US disclosed